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Liver cannabis

CS141 Sethi, N., P. K. Agnihotri and S. Srivastava. Aminopyrine-n-demethy-lase activity of rat liver after adminis- CS152 tration of crude cannabis extract. [Pg.100]

CS163 Soni, C. M. and M. L. Gupta. Effect of cannabis (bhang) extract on blood glucose and liver glycogen in albino rats. Indian J Physiol Pharmacol 1978 22 152-154. [Pg.101]

Toxicity. Cannabis or A -THC intoxication may result in loss of consciousness or even death, but reports of fatalities are rare. In one case of fatal poisoning by A -THC, the following postmortem concentrations of A -THC in tissues were reported liver 37.5 pg/g, kidney 42 pg/g, and spleen 12 pg/g (S. N. Tewari and J. D. Sharma, Toxicol. Lett., 1980, 5, 279-281). [Pg.425]

Cannabinoids are metabolized in the liver. A major metabolite is 11-hydroxy-THC, which is possibly more potent than THC itself and may be responsible for some of the effects of cannabis. More than 20 other metabolites are known, some of which are psychoactive and all of which have long half-lives of... [Pg.405]

The most widespread abuse of cannabis is by smoking. It occasionally may be abused orally. When smoked, initial metabolism occurs in the lungs, whereas this takes place in the liver when marijuana is taken orally. The identification of 9-carboxy-tetrahydrocannabinol (THC) in urine is considered to be the best indication of previous cannabis consumption. Before SPE, alkaline hydrolysis of the sample is necessary to free the metabolite 9-carboxy-THC. Afterward, M,0-bis-trimethylsilyl-trifluoroacetamide (BSTFA) and trimethylchlorodilsne (TMCS) are added for derivatization the product is analyzed by GC-MS in El or negative-ion chemical ionization (NICI) mode. ... [Pg.946]

Jiang R, Yamaori S, Takeda S, Yamamoto 1, Wata-nabe K (2011) Identification of cytochrome P450 enzymes responsible for metabolism of cannabi-diol by human liver microsomes. Life Sci 89 165-170... [Pg.727]

Liver Daily cannabis use may be a susceptibility factor for steatosis in chronic hepatitis C, an important consideration, since steatosis has been reported to increase fibrosis and reduce the rate of viral eradication. In 315 consecutive patients with chronic hepatitis C tmdergoing Uver biopsy collected, the patients were categorized as non-users (64%), occasional users (12%), and daily users (24%) [18. After alcohol intake and viral genot5rpe were controlled for, marked steatosis (at least 30% of... [Pg.58]

Cannabinoids The principal active constituent of Cannabis sativa is A -tetrahydrocannabinol (THC). It is absorbed through the lung during smoking and is rapidly metabolized in the liver to the active metabolite 11-hydroxy-THC, which... [Pg.292]

See other pages where Liver cannabis is mentioned: [Pg.270]    [Pg.88]    [Pg.213]    [Pg.65]    [Pg.84]    [Pg.98]    [Pg.270]    [Pg.321]    [Pg.607]    [Pg.274]    [Pg.405]    [Pg.96]    [Pg.858]    [Pg.662]    [Pg.667]    [Pg.216]    [Pg.450]    [Pg.76]    [Pg.248]    [Pg.60]    [Pg.237]    [Pg.503]    [Pg.305]    [Pg.288]   
See also in sourсe #XX -- [ Pg.94 ]



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