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Cancer malignant tumours cytotoxic

ATLS is potentially a catastrophic complication of chemotherapy in patients with a high tumour load. It results from cytotoxic damage to large numbers of cancerous cells. The DNA and RNA released are broken down to uric acid, which precipitates in the renal tubules causing acute uric acid nephropathy. Recent evidence suggests that recombinant urate oxidase, which converts uric acid to soluble allan-toin, is successful in the treatment and prevention of ATLS in patients with haematological malignancies. [Pg.127]

See other pages where Cancer malignant tumours cytotoxic is mentioned: [Pg.604]    [Pg.412]    [Pg.604]    [Pg.178]    [Pg.314]    [Pg.98]    [Pg.121]    [Pg.213]    [Pg.211]    [Pg.150]    [Pg.364]    [Pg.23]    [Pg.14]    [Pg.226]    [Pg.643]    [Pg.18]    [Pg.572]    [Pg.60]    [Pg.31]   


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Cancer (malignant tumours

Cancer cytotoxicity

Cancer cytotoxics

Malignancy

Malignancy/cancer

Malignant

Malignant tumours

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