Cancer comparative biochemistry

But despite these examples of biochemical evolution and modification in progress, to which more are being added as the science of comparative biochemistry matures, it remains true that the biochemical composition and organization of all the forms of life now present on earth demonstrate unity a unity quite at variance with their more obvious differences in gross structure and behaviour. Most of us would hesitate to compare ourselves with fish, typhoid bacteria, cancer cells, or even oak trees, yet the fact is that we have very much more in common with them than we might have guessed. 

A basic aim of chemotherapy is clearly to obtain a selective effect between a normal host cell and the invading cell, be it bacterial, protozoal, or cancerous. This selectivity may be achieved by differences in distribution, comparative biochemistry, or comparative cytology [1], the damage induced eventually rendering the attacked cell more susceptible to the host s defense mechanisms. 

Chiou, S., Raynor, R.L., Bin, Z., Chambers, T.C., and Kuo, J.F.,1993, Cobra Venom Cardiotoxin (Cytotoxin) Isoforms and Neurotoxin Comparative Rotency of Protein Kinase C Inhibitors and Cancer Cell Cytotoxicity and Modes of Enzyme Inhibition, In Biochemistry, 32, 2062. 

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