Calcium Phosphate, Hydroxyapatite, and Poly d,-lactic acid

4 Calcium Phosphate, Hydroxyapatite, and Poly(d,l-lactic acid) 

Because of their outstanding bioactivity and biocompatibility calcium phosphate-based materials have been widely investigated for applications in the biomedical fields (17). Amorphous calcium phosphate nanospheres and hydroxyapatite nanorods have been prepared and hybridized with poly(d,/-lactic acid) in order to fabricate composite nanofibers using an electrospinning technique. 

The so-prepared composite nanofibers exhibit favorable mineralization behaviors in a simulated body fluid. In the mineralization process, the calcium phosphate nanospheres and the hydroxyapatite nanorods play an important role in the formation of hydroxyapatite nanosheets on the surface of composite nanofibers. The composite nanofibers exhibit a high biocompatibility (17). 

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