Valerian Caffeine

Behavioral effects Several behavioral effects of valerian have been noted in animals. These include suppression of the orienting response in an open-field paradigm, decreasing spontaneous and caffeine-induced motor... 

Solid-liquid extraction is applied on an industrial scale to produce oils and fats from oil-bearing seeds. In the food and flavour industry, extracts and resins, such as hop, chamomile, peppermint, valerian, vanilla, red pepper and liquorice, are obtained from herbs, roots, seeds and drugs. The technology has also found application in the pharmaceutical industry for the extraction of antibiotics, alkaloids and caffeine. 

Inhibits metabolizing enzymes (caffeine inhibits CYPl A2, which metabolizes clozapine). Inhibition of CYP by ginkgo t alpha-1 effects of risperidone. Valerian may worsen the sedative properties of haloperidol. Hops and phenothiazine have been associated with hyperthermia in dogs... 

Valerian root extract does not affect the metabolism of caffeine, chlorzoxazone, debrisoquine and metabolism. 

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