BZ Poisoning

Inhibition of acetylcholine in autonomic and central nervous systems 

Bowel sounds - decreased/absent (ileus, adynamic) 

Mentation - concentration impaired Mentation - confabulation Mentation - confused Mentation - crying, purposeless Mentation - disrobing Mentation - hallucinations Mentation - illusions Mentation - judgement impaired Mentation - memory impaired (amnesia) 

Sweating - decreased Temperature, body - elevated (fever) 

Thirst - excessive Urination force - decreased Vomiting 

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Arsine poisoning Brevetoxin poisoning BZ poisoning Campylobacteriosis Chickenpox Cholera... 

A survey in Britain covering the decade of the 1980s demonstrated large numbers of successful suicides using BZs, either alone or in combination with alcohol (Serfaty et al., 1993 see also Buckley et al., 1995). Serfaty and Masterton (1993) found 891 fatalities with BZs alone and 591 in combination with alcohol. The total of all poisonings attributed to BZs was 1,576 during the 10-year period, putting them ahead of aspirin/ salicylates at 1,308 as well as amitriptyline (1,083) and dothiepin at 981. 

Mullins ME, Horowitz BZ. The futility of hemoperfusion and hemodialysis in Amanita phalloides poisoning. Vet Hum Toxicol... 

Centrally acting anticholinergic. Has an antidepressant effect. Has been considered as an alternative or addition to atropine in the treatment of nerve-agent poisoning. Do not confuse with BZ qv, which also has anti-cholinergic effects. 

The gas phase alkylation of toluene with methanol was carried out in a fixed-bed tubular reactor at atmospheric pressure. Samples were sieved to retain particles with 0.35-0.40 mm in diameter for catafytic measurements. A mixture of toluene/methanol of 1 1 molar ratio was vaporized in a preheating section and delivered to the reactor. The reaction was carried out at 400 °C, employing a space velocity (WHSV) of 2 h. Toluene conversion (Xtoi) was calculated as Xtoi (%) = [EYj / (ZYj + Ytoi.)]100, where ZYj is the molar fiactions of the aromatic reaction products, including benzene, and Ytoi is the outlet molar fiaction of toluene. The selectivity to product j was determined as Sj (%) = [Y/EYj.lOO. The Sei-bz selectivity includes the sum of ethylbenzene and styrene, which are the side-chain alkylation products. In-situ poisoning experiments were carried out by doping the toluene/methanol mixture with either acetic acid or 3,5-dimethyl pyridine in a concentration range between 0-15000 ppm... 

Nerve Agent Proliferation Dynamics of Nerve Agent Poisoning Incapacitants Psychoactive Chemicals in War Belladonna, or Glycolate Alkaloids 3-Quinuclidinyl Benzilate (BZ)... 

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