Butanenitrile, 2-

Butanenitrile, 3-methyI-2-phenyl- [Butyronitrile, 3-methyl-2-phenyl-j, 55, 102 BUTANENITRILE, 2-phenyl- [Butyronitrile, 2-phenyl-], 55,91, 94, 100 Butanethioie acid [Butyric add, thio-], 55, 129,131... 

Butane, 2,3-0-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)-catalyst in homogeneous asymmetric hydrogenation, 6, 781 Butane-1,4-dioic acid, 2,2-di(indolyl)-synthesis, 4, 226 Butanenitrile, 4-hydroxy-dihydropyran synthesis from, 3, 769 Butanoic acid, -y-aryl-y-amino-synthesis, 1, 433 1-Butanol... 

How could you convert butanenitrile into the following compounds Write each step showing the reagents needed. 

BUTANENITRILE, 2-ethenyl-2-phenyl-[Butyromtnle, 2-phenyl-2-vinyl-], 55, 99... 

C 1H15NO2S 3339-36-4) see. Tiemoniuin iodide (2-oxononyl)phosphonic acid dimethyl ester (C11H23O4P 57497-25-9) see Unoprostone isopropyl (S)-4-[[4-[(2-oxo-4-oxazolidinyl)methyl]phenyl]hydrazo-no]butanenitrile... 

Gelo-Pujic, M., Marion, C., Mauger, C. et al. (2006) Biohydrolysis of (S)-3-(thiophen-2-ylthio)butanenitrile. Tetrahedron Letters, 47, 8119-8123. 

Additional studies featuring reactions of thiophene derivatives detail biohydrolysis of (S)-3-(thiophen-2-ylthio)butanenitrile <06TL8119>, lipase catalyzed resolution of thiotetronic acids <06TL7163>, enzymatic kinetic resolution of l,l-dioxo-2,3-dihydrothiophen-3-ol <06TL5273>, and efficient synthesis of 6-methyl-2,3-dihydrothieno[2,3-c]furan 55, a coffee... 

All values are in kilocalories per mole (kcal/mol). Acetonitrile = CH3CN, propanenitrile = C2H5CN, butanenitrile — C3H7CN, pentanenitrile — C4H9CN. 

All values butanenitrile are in reciprocal seconds (s — C3H7CN, pentanenitrile — ). Acetonitrile = C4H9CN, benzene CH3CN, propanenitrile = C6H6. = C2H5CN,... 

Figure 2.4. The normalized rate constants for proton transfer as a function of the negative enthalpy change (—AFkcal/mol) for the solvent butanenitrile. Experimental data = squares. The BH model = solid curve with Es — 1.5kcal/mol, Ea — l.Okcal/mol, q = 200 cm-1, and T — 298 K. 

Figure 2.7. The rate constants for proton transfer as a function of the negative enthalpy change for the three nitrile solvents as a function of Es and otg with the remaining parameters held constant as specified in Figure 2.5. Butanenitrile = squares with Es = 8.0kcal/mol and g>q = 195 cm-1. Propanenitrile = triangles with Es — 12.0kcal/mol and mq = 179cm-1. Acetonitrile = circles with Es — 17.0kcal/mol and cdq = 164 cm-1.

A comparable metabolic pattern was observed in the rat after oral administration of 3-([l,l -biphenyl]-4-yl)butanenitrile (11.84), a nonsteroidal anti-... 

Dehydration of oximes to form nitriles is, again, a rare but intriguing reaction. It has, indeed, been demonstrated that cytochrome P450 (see Chapt. 3 in [50]) is able to transform butanal oxime (11.103, R = H, R = Pr, Fig. 11.14, also 11.72) to butanenitrile by a Beckmann-type dehydration [105] [133]. The reaction is inhibited by the presence of 02, and is catalyzed by cytochrome P450 in its reduced (ferrous) state. 

Martinez, S., Garriga, R., Perez, P.. and Gracia. M. Densities and viscosities of binary mixtures of butanenitrile with butanol isomers at several temperatures. J. Chem. Eng. Data, 45(6) 1182-1188, 2000a. 

Diphenyl telluropyran-4-one (typicalprocedure)7° 120 mL (0.12 mol) of a 1.0 M solution of lithium triethylborohydride in tetrahydrofuran are added to 7.65 g (60 mmol) of powdered tellurium under nitrogen, and the mixture stirred at 20°C for 4 h. A solution of sodium ethoxide (prepared from 5.52 g (0.24 mol) of sodium and 240 mL of absolute alcohol) is added to the dilithium telluride, 13.8 g (60 mmol) of bis(phenylethynyl) ketone are dissolved in a mixture of 150 mL of tetrahydrofuran and 150 mL of 1 M sodium ethoxide in ethanol this solution is poured as quickly as possible into the deep-purple-coloured dilithium telluride soluhon. The flask containing the reaction mixture is immediately placed in a water bath at 50°C and the temperature slowly increased over 30 min until ethanol begins to condense on the side of the flask. The water bath is removed and the mixture is stirred overnight at 20°C. Dichloromethane (400 mL) is then added, the resultant mixture is washed with 800 mL of water, and the organic phase is separated and concentrated to an oil. The oil is dissolved in 600 mL of dichloromethane, and the solution is filtered through a pad of sand. The filtrate is washed with 200 mL of 2% aqueous sodium chloride soluhon, dried with anhydrous sodium sulphate, filtered and evaporated. The brownish solid residue is triturated with 20 mL of butanenitrile and the fine yellow solid is collected by filtration yield 10.9 g (51%) m.p. 126-129°C (from acetonitrile). 

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