Butane, 2-ethoxy

The proposed mechanism for producing ethanol [64-17-5] from butane involves -scission of a j -butoxy radical (eq. 38). The j -butoxy radicals are derived from j -butylperoxy radicals (reaction 14 (213)) and/or through some sequence involving reaction 33. If 25% of the carbon forms ethanol, over 50% must pass through the j -butoxy radical. Furthermore, the principal fate of j -butoxy radicals must be the P-scission reaction the ethoxy radical, on the other hand, must be converted to ethanol efficiently. 

The synthesis of 1-ethoxy-1-butjme has been reported previously, but the preparations have required multistep sequences. Two of the procedures use 1,2-dibromo-l-ethoxy butane which is dehydrohalogenated in two successive steps, first by an amine base and then by either powdered potassium hydroxide or sodium amide no yields are given. The... 

Reactions of carbon nucleophiles with organohalogen compounds have great diversity for the construction of now carbon-carbon bonds. The intriguing synthon, ethoxyethynylsodium, is generated and alkylated in 1-ETHOXY-1-BUTANE. Following an alkylation of propynylsodium, a vinyl halide is generated in a stereoselective manner... 

Craig s synthesis of nicotine (V to VII, p. 42) proceeds via nomicotine. Nicotinic acid nitrile reacts with the Grignard reagent derived from ethyl y-bromopropyl ether to give 3-pyridyl-y-ethoxypropyl ketone (V). This yields an oily oxime (VI) reducible to a-(3-pyridyl)-a-amino-8-ethoxy-w-butane (VII), which with 48 per cent, hydrobromic acid at 130-3° gives womicotine, and this on methylation yields dZ-nicotine. 

Wenn man ahnlich wie oben beschrieben verfahrt, jedoch anstelle von Trifluormethan-sulfonsaure-trimethylsilylester/Casiumfluorid ein reaktives Alkyl-halogenid (1-Jod-butan, Benzyl-bromid, Bromessigsaure-ethylester) verwendet, erhaltman substituierte 1-Alkyl-pyrrolidine1, z.B. l-Butyl-3,4-dimethoxycarbonyl-2-phenyl-pyrrolidin (82%), 1-Benzyl-3,4-dimethoxycarbonyl-2-phenyl-pyrrolidin (79%) oder 3,4-Dinlethoxycarbonyl-1-(ethoxy-carbonyl-methyl )-2-phenyl-pyrrolidin (74%). 

C(CH3)j CHj ch3 ch3 czh5 3-tert.- Butylamino-2,2-di-methoxy-butan 3-tert.-Butylamino-2,2-di-ethoxy-butan 81 33 3-tert. -Butylamino-2-butanon 65 ... 

Dehalogenation and related reactions have also been employed in the synthesis of many bicyclobutanes. Sodium induced dechlorination of l,3-dichloro-2,2,4,4-letramethylcyclobu-tane (69) gave 2,2,4,4-tetramethylbicyclo[1.1.0]butane (70) in 47% yield,29 while magnesium also converted l-chloro-3-ethoxy-l-phenyl-2,2,4,4-tetramethylcyclobutane (71) into 1-phenyl-2,2,4,4-tetramethylbicyclo[1.1.0]butane (72) in 40% yield.31 Other typical preparations are summarized in Table 3 25-29-31 35... 

Butane 1.2-Djchloro-l,2-difluoro-3-ethoxy- El0b2. 147 (Educt) Ethane, 1-tert.-Butyloxy-2,2-... 

Butane 3.4-Dichloro-l-( 1.2-riichIoro-trifluoro-ethoxy)-heptafluoro-E10b,.. 360 (En + C1C E2-CCIF-CF,-CF2-OK)... 

The reaction is performed under dry conditions. 40.5 g l,2-diphenyl-l-[4-[2-(N,N-dimethylamino)ethoxy]phenyl]butane-l,4-diol and 150 ml of acetic acid anhydride are placed in a flask. The temperature is raised to 90°C, where it is kept until the primary OH-group is completely acetylated. [4-Acetoxy-1,2-... 

Before Interrante s studies, synthesis of poly(silylenemethylenes) was limited by the availability of the monomer. It was found that ethoxy substituents on silicon lead to improved yields for the formation of four-membered rings <1996JOM(521)l> (Scheme 19), then ethoxy functionality can be converted into chloride. Therefore disilacyclo-butane monomers became easier to approach. 

Although some carbenes are reported not to add to cyclopropenes207, there are several examples of inter- and intra-molecular addition leading initially to the formation of bicyclobutanes. l,2-Diphenylcyclopropene-3-carboxylates are converted to a mixture of three stereoisomeric bicyclo[1.1.0]butanes by reaction with ethoxy-carbonylcarbene generated from the thermolysis of ethyl diazoacetate an additional product is the diene (278) which is apparently formed by rearrangement of an intermediate zwitter ion208). It should be noted, however, that cyclopropenes readily undergo addition to diazo-compounds, and that subsequent transformations may then lead to bicyclobutanes (see Section 8), and that a free carbene may therefore not be involved in the above process. 

Preparation of 2-(butane-l-sulfonyl)-6-ethoxy-8H-pyrido[2,3-d]pyrimidin-7-one... 

Octafluoro-l- tetrafluoro-l-(trifluoromethyl)ethoxy -4-(trimethylsilyl)butane Typical Procedure ... 

Butan 2-Nitro-l-nitrato- X/l, 310 Ethan l,l-Dinitro-2-ethoxy- El9a. 493 (H -> N02)... 

Butan 2-Chlor-1,4-dibrom-1,1,2-trifluor-4-(2,2,2-trifluor-ethoxy)-E14a/3, 72 (En-OR +... 

Butan 1,4-Bis-[mercapto-thiocarbo-nyloxy]- (Dikalium-Salz) IX, 812 Disulfan Bis-[ethoxy-thiocarbonyl]-E4, 434 (RO-CS-SNa/Oxid.)... 

Cyclobutatn 1,3-Dinitro-l -ethoxy-carbonyl- E17e, 50 (1-COOR — bicyclo[l. 1.0]butan -E N204)... 

Butan 1,2-Diacetoxy-l-ethoxy-Vl/la, 1, 139f., 212, 214 Butandisaure 2-Ethyl-3-hydroxy- -diethylester E21a, 733 (2-H -v 2-C2H5)... 

Butan 2,2-Dichlor-l-diethylamino-l-ethoxy- E14a/2, 278 (Iminium/ R-OH)... 

Butan 2,3-Bis-[l-formyIamino-2,2,2-trichlor-ethoxy]-2,3-dimethyl-El4a/2, 224 (Cl -> OR)... 

Phosphonsaure l-Diazo-3-(3,5-di-oxo-4-methyl-l,2,3-triazolidino)-2-ethoxy-3-methyl-butan- -dimethylester E14b, 1344 (En + — N = N—)... 

C7H15CI 2-chloro-5-methylhexane 58766-17-9 239.33 21.251 2 12213 C7H160 2-ethoxy-2-nnethyl butane 919-94-8 177.80 4.137 2... 

C7H160 2-ethoxy-2-methyl butane 919-94-8 gas 1.541 2 14881 C8H16 trans-1,2-dimethylcycfohexane 6876-23-9 gas 0.000 2... 

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