1,3-Butadiene synthesis

OSTROMISLENSKY Butadiene Synthesis Catalytic butadiene synthesis trom ethanol and acetaldehyda. 

Zamojski A. Chiral (E,E)-l,4-Dialkoxy-l,3-Butadienes. Synthesis, Conformational Studies and Diels-Alder Reactions with Symmetric Dienophiles Chemtracts 2000 13 62-65... 

Adipic acid is prepared commercially by oxidative processes using either benzene or phenol as the raw material base. Since both benzene and phenol prices track with the price of crude oil, future adipic acid price will increase as the oil reserve decreases(j ). Thus, there is a need for a new process to produce adipic acid from cheap, and readily available, raw materials such as butadiene, synthesis gas, and methanol. 

One process that capitalizes on butadiene, synthesis gas, and methanol as raw materials is BASF s two-step hydrocarbonylation route to adipic acid(3-7). The butadiene in the C4 cut from an olefin plant steam cracker is transformed by a two-stage carbonylation with carbon monoxide and methanol into adipic acid dimethyl ester. Hydrolysis converts the diester into adipic acid. BASF is now engineering a 130 million pound per year commercial plant based on this technology(8,9). Technology drawbacks include a requirement for severe pressure (>4500 psig) in the first cobalt catalyzed carbonylation step and dimethyl adipate separation from branched diester isomers formed in the second carbonylation step. 

OSTROMISLENSKY Butadiene Synthesis CatalyHc butadiene synthesis from ethanol and acetaldehyde. 

ORTON Haloaniline rearrangement 282 OSTROMISLENSKY Butadiene synthesis 282 OVERMAN Pyrrolidine synthesis 263... 

Barluenga, J., Suarez-Sobrino, A., Lopez, L. A. Chiral heterosubstituted 1,3-butadienes synthesis and [4+2] cycloaddition reactions. Aldrichimica Acta 1999, 32,4-15. 

Use Solvent, cross-linking agent, polymerization of gasoline, butadiene synthesis, synthesis of C4and C5 derivatives. 

Table 12.7 Variables and experimental domain in the study of trimethylsifyloxy-l,3-butadiene synthesis.

Okauchi, T., Fukamachi, T., Nakamura, F., Ichikawa, J., and Minami, T., 2-Phosphono-l,1,4,4-tetrathio-l,3-butadienes. Synthesis and synthetic application to highly functionalized dienes and heterocycles, Bull. Soc. Chim. Belg.. 106, 525, 1997. 

Janecki, T., A convenient synthesis of substituted 2-cyano-l,3-butadienes, Synthesis. 167, 1991. Ting, P.C., and Solomon, D.M., Synthesis of spiro[4, 5, 10,11-tetrahydro-5//-dibenzo[a,d]cyclohep-ten-5-yl-2 (37/)-furans] as potential cytokine inhibitors, J. Heterocycl. Chem., 32, 1027, 1995. Armesto, D., flail ego, M.G., Horspool, W.M., and Agarrabeitia, A.R., A new photochemical synthesis of cyclopropanecarboxylic acids present in pyrethroids by the aza-di-Jt-methane reanangement. Tetrahedron, 51, 9223, 1995. 

Butadiene Synthesis by Dehydrogenation and Oxidative Dehydrogenation of 2,3-Butanediol... 

Walter Reppe s breakthrough in the butadiene synthesis was central to the new... 

The development of trickle-hed reactors in chemical industry seems to have been closely related to the first industrial processes of butadiene synthesis. 

Trickle-hed reactor has been used for the first time during the twenties in the four step process for butadiene synthesis (see for example reference 6). 

The second step of this butadiene synthesis, the hydrogenation of butynediol, can also use trickle-bed reactors. This will be described below. 

Zhou Y, Zhang WX, Xi Z (2012) 1,3-Butadienylzinctrimer formed via transmetallation from 1,4-dilithio-l,3-butadienes synthesis, structural characterization and application in negishi cross-coupling. Organometallics 31 5546-5550... 

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