Brunner’s glands

Secretin - The scope of physiological activities of secretin has been broadened by recent findings it now seems fairly certain that these activities include stimulation of pepsin secretion and of Brunner s gland secretion,3° Since the availability of natural secretin of great purity and synthetic secretin, investigators have been able to demonstrate that, in contrast to older preparations, pure secretin is effective by the subcutaneous route39 and up to ten times more potent. ... 

Hyperplasia of Brunner s glands is classically seen in the bulb and descending duodenum in the elderly. 

Fig. 5. 21a,b. Brunner s gland adenoma a CECT shows an intussusception in the distal duodenum, b Barium follow-through performed later shows a large filling defect arising from the first part of the duodenum which at operation was confirmed as being due to a Brunner s gland adenoma... 

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