Bromophenyl

Fig. 2. Preparation of precursors for closure to stmcture (24) at the a bond. (25) = 2,4-dichloro-5- uoroacetophenone [704-10-9], (26) = 4-bromo-2,5-difluoroacetophenone [123942-11 -0], (27) = 2,4-dichloro-5-fluoroben2oic acid [86522-89-6], (28) = 4-bromo-2,5-difluoroben2oic acid [28314-82-1] (29) = ethyl 3-(2,4-dichloro-5-fluorophenyl)-3-oxopropanoate(30) = ethyl 3-(2,5-difluoro-4-bromophenyl)-3-oxopropanoate...

C NMR, 7, 498 (79TH51600) 2H-Azepine-4-carboxylic acid, 7-(4-bromophenyl)-3-methoxy-2-oxo-6-phenyl-X-ray, 7, 494 <79H(12)1423> 3H-A2epine-4-carboxylic acid, 6-acetyl-2-ethoxy-3-oxo-7-phenyl-, ethyl ester H NMR, 7, 503 <81H(16)363) 3H-Azepine-4-carboxylic acid, 2,6-diethoxy-3-oxo-7-phenyl-, ethyl ester H NMR, 7, 503 <81H(16)363) 3H-Azepine-4-carboxylic acid, 2-ethoxy-3-oxo-6,7-diphenyl-, ethyl ester HNMR, 7, 503 <81H(16)363) 3H-Azepine-4-carboxylic acid, 2-ethoxy-3-oxo-7-phenyl-, ethyl ester... 

Thiazol-3-ium, 3-ethyl-2-[A -(3 -ethyl-2 -thiazolylidene)-3-ylidene-1 -pro pen]-1 -yl-visible, 1, 345 (B-76MI11201) Thiazolo[2,3-a]isoquinolinium, anhydro-3-(4-bromophenyl)-2-mercapto-X-ray, 6, 669 (67JCS(B)1117)... 

Thiazolo[3,2-a]pyridinium, 3-(4-bromophenyl)-X-ray, 6, 669 (80AX(B)1229) Thiazolo[3,2-a]pyridinium, 3-carboxy-2,3-dihydro-8 hydroxy-5-methyl- C NMR, 6, 678 (82UP42900) Thiazolo[3,2-a]pyridinium, 2,3-dihydro- C NMR, 6, 678 (82UP42900) Thiazolo[3,2-a]pyridinium, 2,3-dihydro-2,5-dimethyl-... 

Thiazolo[2,3-a]isoquinolinium hydroxide, anhydro-3-(4-bromophenyl)-2-mercapto-X-ray diffraction, 6, 669 Thiazololactams fused, 6, 683-684... 

Bromophenyl isothiocyanate [1985-12-2] M 214.1, m 56-58 . Recryst from boiling n-hexane. Any insoluble material is most probably the corresponding urea. It can be purified by steam distn, cool the receiver, add NaCl and extract in Et20, wash extract with N H2SO4 dry (MgS04), evaporate and recrystallise the residual solid. [Org Synth Coll Vol IV 700 7965 Coll Vol 1447 1941.]... 

BROM-O-GAS , methyl bromide, 27 4-Bromophenyl phenyl ether, 27 Bromopropane, 28... 

Chemicel Name (4-bromophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate Common Name Parabromdylamine Structural Formula ... 

Initialiy, 4-bromobenzyl-cyanide is reacted with sodium amide and 2-chloropyridine to give bromophenyl-pyridyl acetonitrile. This is then reacted with sodium amide then dimethyi amino ethyl chloride to give 4.bromophenyl-dimethylamlnoethyl-pyrldyi acetonitrlie. This intermediate is then hydrolyzed and decarboxylated to bromphenirame using 80% H2SO4 at 140°-150°C for 24 hours. The brompheniramine maieate may be made by reaction with maleic acid in ethanol followed by recrystallization from pentanoi. 

Chemical Name 3-(4-Bromophenyl)-l l,l l-dimethyl-3-(3-pyridinyl)-2-propen-1 -amine Common Name —... 

To 9 g of n-butyllithium in 200 ml of dry ether 20 g of 3-bromopyridine Is added as quickly as possible at -40°C without raising the temperature. When the addition Is finished the mixture is stirred for another 30 minutes. Thereafter 32.5 g of 0>dimethylamino-4 -bromopro-piophenone is added in such a way that the temperature does not exceed -40°C. The cooling is discontinued and the mixture is stirred during the night whereupon the reaction mixture is poured onto ice and diluted HCI, which is washed with ether and is extracted with 20 ml of methylene dichloride. The methylene dichloride is dried and evaporated. The crystals are dissolved in water, which then is made alkaline with a solution of Na2C03, is extracted with ether, dried, and evaporated and recrystallized from isopropyl ether, petroleum ether 1 1. Yield 4 g of 1 -(4 -bromophenyl)-3-(N,N-dimethylamino)-1 -(3"-pyridyl)-propanol. Melting point 67°C. 

In another type of mixed ligand oxo-vanadium Schiff base complexes chloro-oxo-bis[N(4-bromophe-nyl) salicylideneiminato] vanadium (V) chelate, VOL2CI, and methoxo-oxobis[N(4-bromophenyl)sali-cylideneimine vanadium (V) chelate, VOL2OCH3 Aiiwi and Salih [43] show that these complexes are active pho-... 

Acetyl-(4-bromomethyl]benzonitrile 9. 2-Acetyl-4-bromophenyl)acetonitrile... 

Although theseazepin-2-onesexhibitdeshieldedprotonresonances(<5 = 7.8 8.2), with an ortho coupling for the 5,6-unsubstituted derivative of J5 6 = 10 Hz, an X-ray structural analysis of ethyl 7-(4-bromophenyl)-3-methoxy-2-oxo-6-phenyl-27/-azepine-4-carboxylate reveals a non-planar azepine ring 48 53 3,5-Dihaloazepin-4-ones have been detected recently in the photolysis of 4-azido-2,6-dihalophenols at 12-14 K.286... 

Bromophenyl trimethylsilyl ether, 41 a-Bromovinyl(triphenyl)silane, 69 Brook rearrangement, 83-4 t-Butoxide-cntalysed condensation, 43 (/ )-4-t-Butyl l-(trimethylsilyloxy)-... 

Pyrazolone, l(4-bromophenyl)-3-methyl-4-(2-methyl-6-carboxyphenylazo)-chromium complex geometrical isomerism, 6, 69 5-Pyrazolone, o-carboxyarylazo-metal complexes geometrical isomerism, 6,68... 

Tris(4-bromophenyl)ammoniumyl hexachloroantimonate (TBPA) differs from the other promoters in that its cation is a radical, and as such produces radical cationic sulfonium ions as glycosylating species from thioglycosides.85 The use of this promoter arose from earlier work on the electrochemical generation of 5-glycosyl radical cations as glycosylating species. 

The reaction rate has also been greatly increased by the addition of a one-electron oxidant tris-(4-bromophenyl)aminium hexafluoroantimonate Ar3N SbF (Ar = / -bromophenyl)." This reagent converts the substrate to a cation radical, which undergoes ring expansion much faster." ... 

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