4- bromo-2- phenyl methyl

N N 3-( p-Bromophenyl)-4-methyl- 1,2,5-oxadiazole 2-oxide 3-(p-bromo-phenyl)-4-methyl-l,2,5-oxadiazole 5-oxide 3,4-diphenyl-l,2,5-oxadiazole... 

Methyl-4-phenyl-2Z/-2,3-benzodiazepin-l(5//)-one (15a) is brominated by /V-broinosuccin-imide in 10 % yield or by trimethylphenylammonium perbromide in 40 % yield to give 5-bromo-2-methyl-4-phenyl-2//-2,3-benzodiazepin-l(5//)-one (16).137... 

Bromo-3-methyl-2-methylene-1 -phenyl-1,2-dihydroquinoxaline 2-Bromomethyl-6-methyl-3-... 

The same heterobifunctional initiator, 2-phenyl-2-[(2,2,6,6-tetramethy-piperidino)oxy] ethyl 2-bromo-2-methyl propanoate, was employed for the synthesis of PMMA-fo-PfBuA-fo-PS triblock terpolymers via the combination of ATRP and NMP [136]. Styrene was initially polymerized through the alkoxyamine function in bulk at 125 °C, leading to PS chains with bromine end groups. Subsequent addition of fBuA in the presence of CuBr/PMDETA provided the PS-fr-PfBuA diblock. Further addition of CuCl, to achieve halogen exchange and MMA yielded the desired triblock copolymer with... 

Capillary gas chromatography is conducted with a cross-linked phenyl methyl silicone stationary phase (5%, 25 m x 0.2 mm x 0.5 pm film thickness, injector temp. 225°C, detector temp. 250°C, column temp. 40-200°C, 15°C/min after 1 min initial time). (Z)-2-Bromo-5-(trimethylsilyl)-2-penten-4-ynoic acid ethyl ester is observed to have a retention time of 14.0 min. GC data for bis(trimethylsilyl)butadiyne is as follows retention time 10.0 min, response factor (GC area produced relative to an equimolar quantity of (Z)-2-bromo-5-(trimethylsilyl)-2-penten-4-ynoic acid ethyl ester) 1.29. For (E)-2-[(trimethylsilyl)ethynyl]-5-(trimethylsilyl)-2-penten-4-ynoic acid ethyl ester the retention time is 17.0 min, the response factor 1.19. 

Chemical cleavage at selective amino acid residues is an alternative method for scission of peptide bonds in target molecules. Cleavage at the Met-Xaa bond is achieved by CNBr, at the Trp-Xaa bond by the tryptophan-directed reagent 3-bromo-3-methyl-2-[(2-nitro-phenyl)sulfanyl]-3//-indole (BNPS-skatole) and at the Asp-Xaa bond by 2% formic acid.123 24 All these reactions are carried out at acidic pH under standard conditions for each reagent. 

MACROCYCLIC POLY AMINES, 58, 86, 90 MACROLIDES, 58, 98 Magnesium, bromo phenyl, 58, 138 Magnesium methyl carbonate, 56, 121 Maleic acid, methyl ester, 56, 63 Manganese, tricarbonyl[(l,2,3,4,5-7))-l-carboxy-2,4-cyclopentadien 1 yl], ... 

To give an impression of the nature of useful experimental results, some flow birefringence measurements which were obtained on a solution of polystyrene in methyl 4-bromo-phenyl carbinol, are reproduced in Figs. 1.2 and 1.3. The concentration of the solution was 2 wt. percents, measuring temperatures are indicated in the figures. The special polystyrene used was a well-known sample of anionically polymerized polystyrene, viz. S 111, provided by the courtesy of Dow Chem. Corp. Its molecular weight is 224,000. The indicated solvent is, at 18 °C, a 0-solvent and possesses practically the same refractive index as polystyrene itself (32). The measurement results are kindly provided by Daum from his still unpublished work. 

Fig. 1.2. Extinction angles % vs. shear rate q for a 2 wt. per cent solution of anionic polystyrene Sill in methyl 4-bromo-phenyl carbinol at the indicated temperatures...

Fig. 1.4 gives such a plot, which was prepared by Philippoff (8,9) from his early measurements on a 15 per cent solution of polyisobutylene (P-100) in decalin (measurement temperatures 30 and 50°C). From this figure it is clearly seen that An as a function of p21 is non-linear. In contrast to the above mentioned solution of S 111 in methyl 4-bromo-phenyl carbinol, the solution of the poly-isobutylene P-100 in decalin does not form a second order fluid. However, for the product A n sin 2%, one obtains a beautiful straight line. The stress-optical law seems to hold also for this more general type of fluid. ... 

Fig. 3.2. Reduced stored free energy Fa vs. reduced shear stress / for a 0.57 wt. per cent solution of Taps. No. 5 in methyl (4-bromo-phenyl) carbinol at various temperatures, viz. ( ) 18°, ( ) 30°, (a) 40° and (A) 50° C (32)...

The data quoted in these figures were obtained on solutions of Taps. No. 5 and S 111 in methyl (4-bromo-phenyl) carbinol. The 0-temperature of these systems is 18° C. In Table 3.2 the intrinsic viscosities of both samples are quoted for four temperatures. The solvent viscosities and densities are given in the lowest two rows. 

This is very remarkable in view of the enormous difference of intrinsic viscosities in methyl (4-bromo-phenyl) carbinol and in bromo-benzene. 

Fig. 3.4. Extrapolation of reduced steady state compliance /, jjto zero concentration for solutions of Sill in methyl (4-bromo-phenyl) carbinol (32). The indicated errors are obtained from all measurements together, irrespective of measurement...

Fig. 4.4. Concentration dependence of reduced steady-state shear compliance J,B for a series of anionic polystyrenes, as mostly provided by Pressure Chem. Corp., Pittsburgh, Pa. Except for the solutions of the three lowest concentrations of S 111 (Dow Chem. Corp.), which were prepared with methyl (4-bromo-phenyl) carbinol and used at various temperatures, all solutions were prepared with mono-bromo-benzene and used at 25° C (32). Measurement temperatures for the melts varied from 196 to 240° C (59). For the molecular weights of the polymers see Table 4.1...

Fig. 5.9. Comparison of extinction angle curves of high molecular weight fractions of polystyrene and cellulose tricarbanilate, using linear scales and reduced shear rate For data on polystyrene Taps. No. 5 and solvents see Table 3.2. (n) Taps. No. 5 in methyl (4-bromo-phenyl carbinol) at 18° C (theta-temperature), (V) the same at 50° C, (o) Taps. No. 5 in monobromo benzene at 25° C, ( ) cellulose tricarbanilate M = 720,000 in benzophenone at 55° C (jy = 4.70 cps) and (a) at...

Malondioate Diethyl (Bromo-difluoro-methyl)-phenyl- ElOa, 558 (Br -4 CR Rf)... 

Bromo-1-(4-bromo-phenyl)-3-nuoro-3-(4-methyl-phenyl)-1 -oxo- ElOa, 239 (En + HF/NBS)... 

Phenyl methyl selenium bromo-iodide, (C6H5)(CH3)SeIBr, is obtained when the dibromide is triturated with a cold solution of potassium iodide of the same concentration. The yield is quantitative, and the product separates from alcohol as red, ill-defined, compact crystals, M.pt. 85° C. with decomposition. Heating at 100° C. causes quantitative decomposition to methyl iodide and bromoselenobenzene, the reaction being represented as follows r... 

X-ray crystal structures, 5, 796 Tetrazole, 5-bromo-l-methyl-reactions, 5, 105, 806 Tetrazole, 5-chloro-solubility, 5, 803 Tetrazole, 5-cyano-2-phenyl-reactions, 5, 820 Tetrazole, 5-cyanovinyl-as propellants, 5, 837 Tetrazole, 1,5-dialkyl-analeptic activity, 5, 834 Tetrazole, 5-dialkylamino-benzylation, 5, 793, 818 Tetrazole, 1,3-diaryl-5-oxide... 

A mixture of 14.91 g (135.324 mmol) of thiophenol and 5.5 g (137.5 mmol) of NaOH in 100 ml acetone was heated at reflux for 2.5 h and then treated dropwise with a solution of 20 g (134.19 mmol) of l-bromo-3-methyl-2-butene in 20 ml acetone. This solution was refluxed for 40 h and then stirred at room temperature for 24 h. Solvent was then removed in vacuo, the residue taken up in water, and extracted with 3 times 50 ml ether. Ether extracts were combined and washed with 3 times 30 ml of 5% NaOH solution, then water, saturated NaCI solution and dried. Solvent was then removed in vacuo and the residue further purified by kugelrohr distillation (80°C, 0.75 mm) to give the phenyl-3-methylbut-2-enylsulfide as a pale yellow oil. 

Bromo-5-methyl-l,6-naphthyridin-2-amine (53) with potassium O-ethylxanthate gave 8-methylthiazolo [4,5-b] L,6]naphthyridin-2(3//)-thione (54) (reactants, l-methylpyrrolidin-2-one, 165°C, 7h >95%) the 3-phenyl analog was made similarly.928... 

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