Brief Psychiatric Rating Scale BPRS

Beck Depression Inventory (Beck) 3. Brief Psychiatric Rating Scale (BPRS) X X... 

Children s Psychiatric Rating Scale. The CPRS is a comprehensive scale to assess a wide range of psychopathologies in children up to age 15. It contains 63 items, with a seven-point scale derived from the Brief Psychiatric Rating Scale (BPRS). This test rates 28 items by direct observation of the child, based on behavior... 

The Brief Psychiatric Rating Scale (BPRS Overall and Gorham, 1962) is an 18-item rating instrument covering a wide range of psychopathology. Ratings are... 

FIG. 5-11. Brief Psychiatric Rating Scale (BPRS) change scores in relationship to trifluoperazine plasma levels. (From Janicak PG, Javaid Jl, Sharma RP, et al. Trifluoperazine plasma levels and clinical response. J Clin Psychopharmacol 1989 9 340-346, with permission.)... 

In 19 patients previously treated with clozapine, olanzapine was used instead (9). Eight were considered to be responders and the rest decompensated, seven of them enough to require hospitalization. Overall Brief Psychiatric Rating Scale (BPRS) scores increased significantly from baseline to final assessment. 

Compared with clozapine, considered the gold standard for treatment of patients with refractory schizophrenia, olanzapine had the same level of efficacy (according to the Positive and Negative Syndrome Scale (PANSS), and the Brief Psychiatric Rating Scale (BPRS)) in 150 patients (mean age, 38 years 60% men) who had failed to respond to conventional neuroleptic drugs because of either insufficient effectiveness or intolerable adverse effects (52). Of these, 147 patients, 52 from Hungary and 95 from South Africa, were randomized to olanzapine (n = 75) or clozapine (n = 72) there were no statistically significant... 

Brief Psychiatric Rating Scale (BPRS) Clinician-rated 18 items, 7-point severity scale score >38 indicates moderate severity The anchored BPRS provides descriptions of each severity rating to increase the interrater reliability. The BPRS has four clusters of symptoms thinking disturbance, anxious depression, withdrawal-retardation, and host i 1 ity-susp ic iou sness... 

A recent study showed abnormal niacin sensitivity in schizophrenia patients as evidenced by attenuation of the flush response to niacin in schizophrenia. However, there is still an ongoing debate whether this response is due to altered pharmacological sensitivity to niacin or an inadequate cutaneous vasodilatory response to the stimulus (Messamore et al. 2003). Early studies even attempted to use niacin as an augmenting agent for the treatment of schizophrenia with mixed results (Ananth et al. 1973 Petrie et al. 1981). In a placebo-controlled comparative study by Ramsay et al. (1970), it was found that, while no significant differences were seen in total Brief Psychiatric Rating Scale (BPRS) scores prior to commencement of the clinical trial, statistically significant... 

---