Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

BRCA-2 mutant

Breast cancer-associated BRCA-1 mutant DNA AuE Chronocoulometiy [Ru(NH3)6] -fM 56... [Pg.125]

SYNTHETIC LETHALITY OF INHIBITING PARP-1 AND PARP-2 IN BRCA MUTANT TUMORS... [Pg.231]

Farmer H, McCabe N, Lord CJ et al (2005) Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434 917-921... [Pg.135]

In 2008, a Phase I clinical trial using MK-4827 was initiated, with a cohort expansion planned in BRCA-1- and BRCA-2-mutant ovarian cancer patients [45]. [Pg.238]

Defects in repair by homologous recombination are associated with inheritance of one mutant allele of the BRCA-1 or BRCA-2 gene and result in predisposition to breast cancer. [Pg.970]

See other pages where BRCA-2 mutant is mentioned: [Pg.238]    [Pg.233]    [Pg.238]    [Pg.241]    [Pg.187]    [Pg.1039]    [Pg.189]   
See also in sourсe #XX -- [ Pg.231 , Pg.232 , Pg.233 , Pg.238 ]



SEARCH



BRCA Mutant Tumors

© 2024 chempedia.info