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Brain glutamate compartments

Location of the Small and Large Glutamate Compartments in the Brain... [Pg.384]

Precursors for the Large and Small Glutamate Compartments m the Brain... [Pg.204]

Van den Berg, C. J. and Garfinkel, D. A simulation study of brain compartments Metabolism of glutamate and related substances in mouse brain. Biochem. J. 23 211-218,1971. [Pg.556]

The forces driving water flow to form cytotoxic edema are osmotic, generated in brain injury conditions (ischemia, trauma, hypoxia) by disturbances in ionic homeostasis due to failure of the Na /K+ ATPase and/or dramatic influx of Na" and Ca " via ionotropic glutamate receptors (excitotoxicity) and other ionic channels. These pathological alterations in cellular ionic homeostasis result in Na" " and water flow from the intravascular and extracellular space into the intracellular compartment. [Pg.133]

B3. Berl, S., Takajaki, G., Clarke, D. D., and Waelsch, H., Metabolic compartments in vivo. Ammonia and glutamic acid metabolism in brain and liver. J. Biol. Chem. 237, 2562-2570 (1962). [Pg.137]

Fig. 2. The simple two-compartment model in brain. The two compartments are connected through the flow of glutamine from the small to the large compartment and by the transport of glutamate and GABA from the large to the small compartment. Fig. 2. The simple two-compartment model in brain. The two compartments are connected through the flow of glutamine from the small to the large compartment and by the transport of glutamate and GABA from the large to the small compartment.
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