Bonding agents biocompatibility

Causton, B. E. (1982). Primers and mineralizing solutions. In Smith, D. C. Williams, D. F. (eds.) Biocompatibility of Dental Materials. Volume II. Biocompatibility of Preventive Dental Materials and Bonding Agents, Chapter 7. Boca Raton, Florida CRC Press Inc. 

It is useful to divide the analysis into mechanical and nonmechanical properties. We will first consider the wear resistance and compressive strength considerations, then see if potential materials will meet the aesthetic, bonding, and biocompatibility criteria. It may be possible to incorporate secondary materials such as colorants, bonding agents, and compatiblizers that address these issues. 

Bonding agents, by their nature, are used on relatively inert tissue, the dentine, and in close proximity to very delicate soft tissue, namely the pulp. For this reason, the question of their biocompatibility is complex, as well as being important [4],... 

Biocompatibility is defined as the ability to perform with an appropriate host response in a specific location (Williams 1987). Its study is complex and beyond the scope of this chapter, but it needs to be considered briefly in the context of the use of bonding agents in clinical dentistry. The tissues involved range in sensitivity from the completely inert (enamel) to the... 

An important feature controlling the biocompatibility of bonding agents is the permeability of the dentin and also its thickness. This will determine whether or not monomers diffuse all the way through to the pulp and whether they arrive at sufficiently high concentrations to cause damage. 

Sodium hyaluronate, or HA, is a biocompatible polysaccharide that is encountered in medicine and the cosmetics industry. Its macroscopic properties are highly sensitive to its hydration level, which is the reason why it has been the object of many studies. When in its dried state, or scarcely hydrated, it is stiff. In this state it may act as a skin-stiffening agent, smoothing wrinkles for instance. When highly hydrated, it acts as a lubricant that is found in synovial fluid. The elucidation of its hydration mechanism has shown us the role of the developing H-bond network in the change of its properties and, at the same time, the power and sensitivity of IR spectrometry to observe water molecules in macromolecules. 

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