Bond properties, relations between

Apart from the isomeric relation between 7 and 1, the appearence of the ternary associate now showing coordinatoclathrate properties gives a reasonable motive for putting up these compounds for discussion here. The dimer formation of carboxylic acids known from the related inclusions of 1 and 26 does not occur here. Instead, one observes a well-balanced system of H-bonds between groups of different acid/base properties. It is left to future studies to find other acid/base combinations which give a comparable situation. Actually, such H-bonded systems remind one of the multiple non-bonded interactions at the active centers of enzymes. 

Hydrogen bonding is now seen as an important property related to membrane permeation. Various scales have been developed [23]. Some of these scales describe total hydrogen bonding capability of a compound, while others discriminate between donors and acceptors [24]. It has been demonstrated that most of these scales show considerable intercorrelation [25]. 

The principal interest of the rubber hydrochloride structure (apart from its bearing on the theory of the relation between the physical properties and the molecular structure of polymers) is that it formed the first test of validity and usefulness of the principle of staggered bonds. Abnormal structures f In all the structures considered so far two... 

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