Blood groups, antigenic determinants types

Synthesis of Type 2 Human Blood Group Antigenic Determinants. The H, X and Y Haptens and Variations of the H Type 2 Determinants as Probes for the Combining Site of the Lectin 1 of Ulex europaeus, O. Hindsgaul, T. Norberg, J. LePendu, and R. U. Lemieux, Carbohydr. Res., 109 (1982) 109-142. 

Geno- type Phenotype Blood group antigens on red cells (minimal determinant structure) Antibodies in plasma Giycosyitransferases in plasma... 

The agglutination of incompatible red blood cells, which indicates that the body s immune system has recognized the presence of foreign cells in the body and has formed antibodies against them, results from the presence of polysaccharide markers on the surface of the cells. Types A, B, and 0 red blood cells each have characteristic markers, called antigenic determinants, type AB cells have both type A and type B markers. The structures of all three blood-group determinants are shown in Figure 25.15. 

---