Blood glucose control in diabetics

Hamura, M., H. Yamatoya, and S. Kudo. Glycerides Rich in Gonjugaed Linoleic Acid (CLA) Improve Blood Glucose Control in Diabetic c57blks-lepr/lepr Mice. Journal of Oleo Sci. 50 889-894 (2001). 

Siddiqui, 0., Shi, W. M., and Chien, Y. W., 1987a, Transdermal iantophoretic delivery of insulin for blood glucose control in diabetic rabbits, Proc. Ini Symp. Control. Rel. Bioact. Mater. A llA. 

The demonstration in 1921 that insulin lowered the blood glucose level in diabetic dogs and humans led to the inference that its main function was the control of the blood glucose level. However, once the diversity of its effects was discovered, it was realised that its major... 

Colombel A, Murat A, Krempf M, Kuchly-Anton B, Charbonnel B. Improvement of blood glucose control in Type 1 diabetic patients treated with lispro and multiple NPH injections. Diabet Med 1999 16(4) 319-24. 

Van Gaal LF, Van Acker KL, De Leeuw IH. Repaglinide improves blood glucose control in sulphonylurea-naive type 2 diabetes. Diabetes Res Clin Pract 2001 53(3) 141-8. 

The effects of pancreatic exocrine supplements (four capsules with meals, two with snacks each capsule containing lipase 10 000 units, protease 37 500 units, amylase 33 200 units) on glucose metabolism have been studied in a 2-week parallel, randomized, placebo-controlled trial in 29 patients with chronic pancreatitis who had stool fat excretion of over 10 g/day, 18 of whom were diabetic and 15 of whom were malnourished (902). There were major problems with blood glucose control in 28 of the 29 patients. 

Home PD, Lindholm A, Riis A European Insulin Aspart Study Group. Insulin aspart vs. human insulin in the management of long-term blood glucose control in type 1 diabetes meUitus a randomized controlled trial. Diabet Med 2000 17(11) 762-70. 

A meta-analysis of 16 clinical studies showed a benefit of intensive blood glucose control in patients with type 1 diabetes as evidenced by a reduction in the frequency, severity, and a delay in the development or progression of diabetic comphcations including nephropathy. The Epidemiology of Diabetes Interventions and Complications study, which observed the DCCT subjects for an additional 4 years while they were receiving care from primary physicians, showed a continued benefit of IIT on the risk of nephropathy as defined by the development of microalbuminuria (53% odds ratio reduction in microalbuminuria). ... 

L14. Little, R. R., Wiedmeyer, H.-M., England, J. D., Knowler, W. C., and Goldstein, D. E., Measurement of glycosylated whole-blood protein for assessing glucose control in diabetes Collection and storage of capillary blood on filter paper. Clin. Chem. 31, 213-216 (1985). 

R. S. Parker, F. J. Doyle, and N. A. Peppas, "A model-based algorithm for blood glucose control in type I diabetic patients," IEEE Transactions on Biomedical Engineering, vol. 46, no. 2, pp. 148-157, Feb 1999. 

Once the blood glucose values in the treated animals had returned to the high, diabetic levels, a second injection of insuUn-containing microspheres again reduced these levels to normal for about 5 more days. It is therefore possible to incorporate labile biological products into the polyanhydrides and to release them in a biologically active form. At the same time, this release can be sustained over a period of time in a controlled fashion. 

UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998 352 837-853. 

Intensified metabolic control, especially in case of diabetes, demands minimal-invasive or non-invasive methods of analytical measurement. For this goal, a method has been developed to measure the blood glucose content in vivo, in direct contact with the skin, by means of diffuse reflection near infrared (NIR) spectroscopy on the basis of multivariate calibration and neural networks (Muller et al. [1997] Fischbacher et al. [1997] Danzer et al. [1998]). Because no patients with any standard blood glucose value are available in principle, a method of indirect calibration has... 

ADVANCE Collaborative Group Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008 358 2560. Baggio LA et al Biology of incretins GLP-1 and GIP. Gastroenterology 2007 132 2131. [PMID 17498508]... 

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