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Blockade of Chemokine Receptors As a Strategy for Antiretroviral Therapy

Blockade of Chemokine Receptors As a Strategy for Antiretroviral Therapy [Pg.89]

Such strategies offer promise for a new generation of antivirals. The rarity of infection of CCR5 A32 homozygotes with X4 strains argues that concurrent administration of CXCR4 blockers will only occasionally be necessary. Further strategies of chemokine blockade in anti HIV therapy are discussed in Chapter 9. [Pg.89]

McFadden G, Murphy PM. Host-related immunomodulators encoded by DNA viruses. Curr Opin Microbiol 2000 3 371-378. [Pg.90]

Murphy PM. Viral exploitation and subversion of the immune system through chemokine mimicry. Nature Immunol 2001 2 116-122. [Pg.90]

Alcami A, Koszinowski UH. Viral mechanisms of immune evasion. Immunol Today 2000 21 447-455. [Pg.90]




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A strategy

A, receptor

A-chemokines

Antiretroviral therapies

Antiretrovirals

Blockade

Chemokines receptors

Receptors blockade

Receptors for

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