Blending processes, affecting factors shape

Overall, factors that might affect the adsorption of actives on the carrier surface include surface properties, moisture content, the type and particle size/shape of carriers and actives, as well as the mixing ratio of actives and carriers. Pharmaceutical processes (i.e., milling and granulation) could affect the adsorption process by altering carrier and active properties (i.e., surface properties, size, and shape), hence the characteristics of blending and the quality of the final dosage form. 

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