Traumatic brain injury blast-induced

FIGURE 13.2 Progression of bTBI. The sequela of events after blast overpressure exposure. Blast-induced traumatic brain injuries follow a sequence of events. Initial tissue damage from the force of blast waves lead to an evolutionary period of changes in biochemical... 

Balakathiresan, N., Bhomia, M., Chandran, R., et al., 2012. MicroRNA let-7i is a promising serum biomarker for blast-induced traumatic brain injury. J. Neurotrauma 29 (7), 1379-1387. 

Nakagawa, A, Manley, G.T., Gean, A.D., et al., 2011. Mechanisms of primary blast-induced traumatic brain injury insights from shock-wave research. J. Neurotrauma 28 (6), 1101-1119. 

In recent military conflicts, the incidence of explosive blast-induced traumatic brain injury (TBI) has substantially increased. BBB disruption associated with TBI results in brain edema and increased cerebrovascular permeability, both of which affect morbidity and mortality in patients with head injury (Ling et al., 2009 Shetty et al., 2014). Brain edema after TBI is thought to be initiated by BBB rupture, permitting the influx of... 

Rubovitch, V, Ten-Bosch, M., Zohar, O., et al., 2011. A mouse model of blast-induced mild traumatic brain injury. Exp. Neurol. 232 (2), 280-289. 

Shetty, A.K., Mishra, V, Kodali, M., et al., 2014. Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves. Front. Cell. Neurosci. 8,1-10. 

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