Blaschke

G. Blaschke, Substituted polyacrylamides as chiral phases for the resolution of drugs in Chromatographic chiral separations, M. Zief, L. J. Crane (Eds.), Chromatographic Science Series, Vol. 40, Marcel Dekker, New York (1988) Chapter 7. 

Figure 5.54 Structures of Praziquantel and its metabolites, cis- and fraw5-4-hydroxy-praziquantel. Reprinted from 7. Chromatogr., B, 708, Lerch, C. and Blaschke, G., Investigation of the stereoselective metabolism of Praziquantel after incubation with rat liver microsomes by capillary electrophoresis and liquid chromatography-mass spectrometry , 267-275, Copyright (1998), with permission from Elsevier Science.

Fig. 1. Methods of Huggins (positive slope), Kraemer (negative slope) (a), Schulz-Blaschke (b), and Martin (c). Data obtained from experimental measures for gelatin B at 37.4°C.

Method Huggins Kramer Schulz- Blaschke Martin... 

The intrinsic viscosity data calculated from the methods of Fluggins, Kramer, Schultz-Blaschke and Martin are shown in Table 1, and how to perform these steps are shown in Figure 1. 

Schulz, G. V. and Blaschke, F. (1941) Eine Gleichung zur Berechnung der Viskositatszahl fur sehr kleine Konzentrationen. J. Prakt. Chem., 158 (1941) 130-135. 

Boffito M, Back DJ, Blaschke TF, Rowland M, Bertz RJ, Gerber JG, Miller V (2003) Protein binding in antiretroviral therapies. AIDS Res Hum Retrovimses 19 825-835 Bressanelli S, Tomei L, Roussel A, Incitti 1, Vitale RL, Mathieu M, De Francesco R, Rey FA (1999) Crystal stmcture of the RNA-dependent RNA polymerase of hepatitis C vims. Proc Natl Acad Sci USA 96 13034-13039... 

Blaschke K, Valencia A. Can bibliographical pointers for known biological data be found automatically Protein interactions as a case study. Comp Funct Genom 2001 2 196-206. 

Blaschke S, Middel P, Domer BG, et al. Expression of activation-induced, T cell-derived, and chemokine-related cytokine/lymphotactin and its functional role in rheumatoid arthritis. Arthritis Rheum 2003 48(7) 1858-1872. 

T. F. Blaschke, Protein binding and kinetics of drugs in liver disease, Clin. Pharmacokinet, 2, 32-44 (1977). 

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