Birth control patches

Birth control hormones can also be delivered through the skin using a skin patch. Of 800,000 women using the patch, however, i about a dozen have died from blood clots believed to be related to the patch. Is this an acceptable risk Consider that pregancy itself poses significant risks. In developed nations, for every 100,000 live births there are about 20 maternal deaths. In the developing nations of sub-Saharan Africa, by contrast, the number of maternal deaths per j 100,000 live births is around 920. 

Skin patches are adhesive patches which contain a reservoir of the drug to be administered. The drug slowly passes from the patch through the skin and into the bloodstream. They are commonly used in hormone replacement therapy, nicotine replacement therapy, pain relief, relief of symptoms of angina, motion sickness, birth control and in the treatment of attention deficit hyperactivity disorder (ADHD). 

Hitchens K. Birth control now comes in a patch for women. Drug Topics 2002 19. 

No current device meets all of these parameters. Diffusion-controlled release is demonstrated by transdermal patches e.g., birth-control, nicotine, etc.), whereas particulates such as metallic micro-/nanoparticles have been used to ablate cancer cells by localized heating with near-IR light.Whereas normal blood vessels have pore sizes <100 nm, the vessels adjacent to cancer cells have pore sizes between 100 and 200 nm. Hence, if DDS particulates e.g.y liposomes, polymeric micelles, metallic nanoparticles) are of this size regime, they will automatically situate nearby cancer cells. However, it usually takes at least 1 day of blood circulation to accumulate sufficient amounts. In order to hide the particles from the immune system, the particulates must be covered with a stealth lipsome such as poly (ethyleneglycol), PEG otherwise, the particulates will be filtered out of the body via the liver as urine. 

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