Biotechnological production using glycerol

Raj, S.M., Rathnasingh, C., Jrmg, W.-C., Park, S., 2009. Effect of process parameters on 3-hydroxypropionic add production from glycerol using a recombinant Escherichia coli. Applied Microbiology Biotechnology 84 (4), 649-657. 

VAPs and its recycling into lipids and/or fats by various microbes. Biotechnological processes have been studied extensively for years, wifh a number of differenf microorganisms, to use glycerol as a carbon source for bioconversions. Some of the useful chemicals thaf can be produced by bioconversions include 1,3-PDO, succinic acid, citric acid, and PHAs (Koutinas et al., 2007), while the production of other chemicals is still being explored. 

Lee, PC., Lee, W.G., Lee, S.Y., et al., 2001. Succinic add production with reduced by-product formation in the fermentation of Anaewbiospirillum succmicipmducens using glycerol as a carbon source. Biotechnology and Bioengineering 72,41-48. 

The production of 1,3-PDO from biomass has been commercialized by DuPont, which has established biotechnological routes for the production of 1,3-PDO from sugars or glycerol [124]. 1,3-PDO is currently used for the production of the PPT fibre commercialized under the brand name Sorona and being used in applications like clothing, residential carpets, and automotive fabrics. Polyethers based upon 1,3-PDO are being used in the production of polyols for polyurethanes [125]. 

Biebl, H., 1991. Glycerol fermentation of 1,3 prpanediol by Clostridium fcufyricura-measurement of product inhibition by use of a pH auxostat. Applied Microbiology and Biotechnology 35, 701-705. 

Gonzalez-Pajuelo, M., Andrade, J.C., Vasconcelos, I., 2004. Production of 1,3-propanediol by Clostridium hutyricum VPI 3266 using a synthetic medium and raw glycerol. Journal of Industrial Microbiology and Biotechnology 31, 442-446. 

Jun, S., Moon, C., Kang, C., et al., 2010. Microbial fed-batch production of 1,3-propanediol using raw glycerol with suspended and immobilized Klebsiella pneumoniae. Applied Biochemistry and Biotechnology 161,491-501. 

Mu, Y, Teng, H., Zhang, D.-J., et al., 2006. Microbial production of 1,3-propanediol by Klebsiella pneumoniae using crude glycerol from biodiesel preparaHons. Biotechnology Letters 28,1755-1759. 

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