Biosynthesis of glucosinolates

WALLSGROVE, R.M., BENNETT, R.N., The biosynthesis of glucosinolates in Brassicas. In Amino Acids and Their Derivatives in Higher Plants, (R.M. Wallsgrove, ed.), Cambridge University Press, Cambridge. 1995, pp. 243-259. 

DU, L., HALKIER, B.A., Biosynthesis of glucosinolates in the developing silique walls and seeds of Sinapis alba., Phytochemistry, 1998,48,1145-1150. 

Bennett, R.N., Donald, A.M., Dawson, G.W., Hick, A.J. and Wallsgrove, R.M. (1993) Aldoxime-forming microsomal enzyme systems involved in the biosynthesis of glucosinolates in oilseed rape leaves. Plant Physiol., 102, 1307-12. 

GRASER, G., SCHNEIDER, B., OLDHAM, N.J., GERSHENZON, J., The methionine chain elongation pathway in the biosynthesis of glucosinolates in Eruca. saliva (Brassicaceae)., Xrc/i. Biochem. Biophys., 2000,378, 411-419. 

NAUR, P., PETERSEN, B.L., MIKKELSEN, M.D., BAK, S RASMUSSEN, H., OLSEN, C.E., HALKIER, B.A., CYP83A1 and CYP83B1, two nonredundant cytochrome P450 enzymes metabolizing oximes in the biosynthesis of glucosinolates in Arabidopsis., Plant Physiol., 2003, 133, 63-72. 

Fig. 2. Glucosinoiate. Proposed routes for the biosynthesis of glucosinolates and cyanogenic glycosides from amino acids.

Nafisi M, Sonderbye IE, Hansen BG, Geu F, Eldin HHN, Nielsen MHN, Jensen NB, Li J, Halkier BA (2006) Cytochromes P450 in the biosynthesis of glucosinolates and indole alkaloids. Phytoehem Rev 5 331-346... 

Cyanogenic glycosides (Table 16.22) are present in lima beans and in some other plant foods. Precursors of cyanogenic glycosides are the amino acids listed in Table 16.22. As in the biosynthesis of glucosinolates (cf. 17.1.2.6.5), an aldoxime is initially formed, which is then transformed into... 

Biosynthesis of glucosinolates (reaction 17.10) starts from the corresponding amino acids, and proceeds via an oxime (I) and thiohydroximic acid (III). The intermediate reactions between... 

Biosynthesis.—Experimental work aimed at clarifying the biosynthesis of glucosinolates was initiated about 10 years ago. By 1968, when a detailed review... 

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