Biosensors Using Atomic Force Microscopes

Biosensors using atomic force microscopes (AFMs) are devices which employ an atomic force microscope for biological recognition events. The principle of biosensors using atomic force microscopy is mainly based on the mass-sensitive detection of binding events that change the deflection of a cantilever whose surface is modified with immobilized bioreceptors. 

Biosensors Using Atomic Force Microscopes, Fig. 1 (a) Basic components and working principle of AFM. A sharp tip fixed at the end of a fiexible cantilever is raster scanned over the surface of a sample. As the tip interacts with the surface, the cantilever deflects, and its deflections are monitored by a laser and a photodiode and then used to reconstruct the topography of the sample, (b) A schematic diagram of AFM as a biosensor in detecting... 

Biosensors Using Atomic Force Microscopes Fluorescence Measurements... 

Biosensors using atomic force microscopes (AFMs) are devices which employ an atomic force microscope for biological recognition events. The principle of biosensors... 

Biosensors Using Atomic Force Microscopes, Figure 3 (a) SEM image and schematic top view of an AFM-tip-integrated frame electrode (b)... 

Biosensors Using Atomic Force Microscopes, Rgure 4 (a) Reactions for giucose detection with a biosensor based on glucose oxidase (GOD),... 

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