Biosensors SERS substrates

Dinish, U.S., Yaw, F.C., Agarwal, A., and Olivo, M. (2011) Development of highly reproducible nanogap SERS substrates comparative performance analysis and its application for glucose sensing. Biosensors Bioelectronics, 26, 1987-1992. 

Fang, C., Agarwal, A., Buddharaju, K.D., Khalid, N.M., Salim, S.M., Widjaja, E., Garland, M.V., Balasubramanian, N., and Kwong, D.L. (2008) DNA detection using nanostructured SERS substrates with rhodamine B as Raman label. Biosensors Bioelectronics, 24, 216-221. 

C. Song, et al.. Highly sensitive immunoassay based on Raman reporter-labeled immu-no-Au aggregates and SERS-active immune substrate, Biosensors and Bioelectronics 25 (4) (2009) 826-831. 

Cancer diagnostics often needs a discrimination of genomic mutations in DNA sequences or special NA structures (miRNA) which can cause various diseases including cancer. SERS technique is very promising for mutation and single nucleotide polymorphisms detection because of the possibility of spatial multiplexing at array format linked with a portable biosensor device. Mahajan and co-workers reported such SERS-based approach using Au substrates prepared by... 

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