Bioregulator synthesis

Mori K (2000) Chemoenzymatic synthesis of pheromones, terpenes, and other bioregulators. In Patel RN (ed) Stereoselective biocatalysis. Marcel Dekker, New York, p 59... 

Economic impacts associated with "off-fiavors" have encouraged research into the bioregulation of geosmin and MIB synthesis. Although this chapter focuses primarily upon controlling geosmin production in the context of the channel catfish aquacultiue industry, the approaches discussed may have relevance in the control of undesirable metabolites in other systems. 

Biofunctional natural products with low molecular weights are classified as shown in Table 1.1. Chemical studies on vitamins, hormones and antibiotics started in the first half of the 20th century, while those on semiochemicals began in the middle of the 20th century. This book treats the chemical synthesis of hormones, pheromones and other bioregulators such as allelochemicals. 

Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Kenji Mori 2010 John Wiley Sons, Ltd... 

One may think that there is no need for the synthesis of biofunctional molecules, because they always exist in organisms, and can be extracted and isolated. This is quite untrue, because the amounts of biofunctional molecules in organisms are usually very small. Due to their extremely low concentrations effective in organisms, biofunctional molecules can be isolated only in very small amounts, as shown in Table 1.2. It is therefore impossible to isolate hormones, pheromones and other bioregulators in gram quantities. 

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