Mori, Kenji

The authors then used a modification of their Lipase-AK route to produce the natural enantiomer, as described in detail in the chapter by Kenji Mori in this volume. Instead of using the enzyme to execute a stereoselective monohydrolysis of meso diacetate 140, the enzyme was used to esterify selectively one of the hydroxy groups of meso diol 128, resulting in the antipodal hydroxyester. After oxidation of the free hydroxyl to the acid, and recrystallization of its salt with (JR)-l-naphthylethylamine, the purified acid was then carried through the remaining steps to furnish the chiral pheromone compound (see the chapter by Kenji Mori in this volume). 

Kenji Mori and Hideto Mori 56 YEAST REDUCTION OF 2,2-DIMETHYL- CYCL0HEXANE-1,3-DI0NE (S)-(+)-3-HYDROXY-2,2-OIMETHYL-CYCLOHEXANONE... 

Kenji Mori, The University of Tokyo, Tokyo, Japan 2010 Elsevier Ltd. All rights reserved. 

Takuya Tashiro, Kenji Mori, Tetrahedron Asymmetry 2005, 16(10), 1801-1806. 

Kenji Mori was born in 1935. In all, he spent 42 years at the University of Tokyo. He holds B.Sc. (agricultural chemistry, 1957), M.Sc. (biochemistry, 1959), and Ph.D. (organic chemistry, 1962) degrees. He was appointed as assistant professor in the Department of Agricultural Chemistry at the University of Tokyo (1962), and was promoted to associate professor (1968) and professor (1978—95). Currently, he is Professor Emeritus. Dr. Mori worked for 7 years (1995—2001) as a professor at the Science University of Tokyo. At present, he is a research consultant at RIKEN (Institute of Physical and Chemical Research) and at... 

Chemical Synthesis of Hormones, Pheromones and Other Bioregulators Kenji Mori 2010 John Wiley Sons, Ltd... 

Chemical synthesis of hormones, pheromones, and other bioregulators / Kenji Mori, p. cm. 

Submitted by Kenji Mori and Hldeto Mori.1 Checked by Mark Hopkins and Larry E. Overman. 

Kenji Mori (1), Glycosphingolipid Synthesis Group, Laboratory for Immune Regulation, Research Center for Allergy and Immunology (RCAI), RKEN, Wako-shi, Saitama, Japan... 

One of the shortest syntheses of an enantiomerically pure pheromone comes from Kenji Mori. [192] The key building blocks of the synthesis are (3H)-meth-yl-4-butanolide, available from Mitsubishi Rayon Co., and (S)-citronellal, which are coupled byway of a corresponding organolithium reaction. The overall yield comes to 16%. 

At the same time, Kenji Mori published a similar route to (+)-disparlure. [195] Since disparlure may virtually be buUt up from the other end, for the Sharpless epoxidation diethyl (L)-tartrate is used instead of the (D)-enantiomer. Byrecrys-taUisation of the 3,5-dinitrobenzoate, the desired enantiomer of the intermediate can be enriched. EnantiomericaUy pure (+)-disparlure is finally obtained by chain extension with lithium dinonylcuprate. 

Professor Kenji Mori of the Science University of Tokyo has been the leading researcher in the study of chirality in insect pheromones [15]. While teaching Pasteur s very first experiments on stereochemistry to undergraduate organic chemistry students in 1973, Professor Mori realized that he could use the two forms of tartaric acid to synthesize the two enantiomers of the compound brevicomin that are drawn in Figure 4.7. In collaboration with colleagues at the University of California (UC) Berkeley, he was amazed to see how attractive (-1-)-brevicomin was to western pine beetles, and how uninterested... 

Department of Biosciences and Informatics, Keio University, Yokohama, Japan Kenji Mori... 

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