Biomolecules protein

Watson, J. D., ed., 1987. Evolution of catalytic function. Cold Spring Harbor Symposium on Quantitative Biology 52 1- 955. Publications from a symposium on tlie nature and evolution of catalytic biomolecules (proteins and RNA) prompted by tlie discovery that RNA could act catalytically. 

Molecular dynamics (MD) simulation has been broadly used for exploration of structure dynamics of biomolecules, protein/DNA interaction, and the effect of solvent as well as interaction between CNTs and biomolecules. 

The chemical modification of CNTs can be endohedral (inside the cavity of the tube) or exohedral [42]. There are some examples in the literature that have demonstrated the filling of CNTs with fullerenes, biomolecules (proteins, DNA), metals and oxides that have been driven inside by capillary pressure [39, 42, 72-78]. However, in this section we will focus on exohedral functionalization, taking place just at the external walls of the tubes. Both covalent (chemical-bond formation) and noncovalent (physiadsorption) functionlizations can be carried out. In the following... 

This author and coworkers at Beckman Coulter first described the use of a low form 96-well plastic microplate for automated micro-ELISA immunoassays (Matson et al., 2001). The polypropylene plate was first modified by a radiofrequency plasma amination process (Matson et al., 1995) followed by conversion to an acyl fluoride surface chemistry for rapid covalent attachment of biomolecules. Proteins (1 to 2 mg/mL) were prepared in 50 mM carbonate buffer, pH 9, containing 4% sodium sulfate (to improve spot uniformity) and printed using a conventional arrayer system. Approximately 200-pL droplets of monoclonal antibodies (anti-cytokine) were deposited into the bottom of the microwells using a Cartesian PS7200 system equipped... 

This technique is widely used on water-soluble biomolecules—proteins, peptides, and carbohydrates in particular. The result is a spectrum whose major peaks consist of the molecular ion with a different number of charges attached. A molecular ion of, for example, about 10,000 Da with a charge (z) of 10 would behave in a mass spectrometer as though its mass were about 1000 daltons. Its mass, therefore, can be determined with a spectrometer of modest resolution—and cost. 

The ultimate goal of chemistry is to understand the world around us on a molecular level, and a knowledge of biochemistry—the chemistry of living organisms—is a crucial part of that goal. In this chapter, we ll look at the main classes of biomolecules proteins, carbohydrates,... 

We will focus our attention in this chapter on an overview of the thermodynamic analysis of metabolism and of the stabilities of two types of biomolecules, proteins and nucleic acids. Rather than provide a comprehensive account of thermodynamic applications to biological systems, we have chosen these two key areas where, historically, thermodynamic measurements have... 

To calculate the geometries and energies of very large molecules, usually polymeric biomolecules (proteins and nucleic acids). 

To Calculate the Geometries and Energies of Very Large Molecules, Usually Polymeric Biomolecules (Proteins and Nucleic Acids)... 

Abstract Among biomolecules, proteins fulfil the most diverse roles. Recent advances... 

Examples of NMR studies of the four classes of biomolecules (proteins, nucleic acids, lipids, and carbohydrates) are described in the next sections. Each class has unique characteristics, so they will be discussed separately. 

We ve now covered two of the four major classes of biomolecules—proteins and carbohydrates—and have trvo remaining. We ll cover Lpids, the largest and most diverse class of biomolecules, in this chapter, looking both at their structure and function and at their metabolism. 

Recognizing and distinguishing the structures of the major classes of biomolecules (proteins, lipids, carbohydrates, nucleic acids)... 

Before dealing with the adsorption of biomolecules (proteins and nucleic acids) onto latex particles, we should recall certain aspects (which will not be defined here) of the adsorption of macromolecules on solid-liquid interfaces. Biomolecules are complex macromolecules in nature, which in... 

Adsorption properties of biomolecules (proteins, lipids, polysaccharides), and a range of techniques for studying such properties, are discussed in... 

Figure 9 Growth in the number of biomolecule (protein and RNA) structures solved by NMR by year. Data from the Protein Data Bank ...

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