Biomedical implications

S.S. Wachtel, G. Wachtel and D. Nakamura, in Vertebrate Endocrinology. Fundamentals and Biomedical Implications. Part B. Reproduction, ed. P. K. T. Pang and M. P. Schreibman, Academic Press, London, 1991, p. 149. 

Considerable evidence for opioid-chemokine interactions comes from studies of pain and inflammation, where the inherent relationships between pain, inflammation, and the counteracting antinociceptive influences of opioids have considerable biomedical implications. The adaptive changes in immune and nervous system function with chronic inflammation and pain further reveal the inherent interrelatedness between opioids (Ossipov et al. 2003 Evans 2004 Roy et al. 2006 Christie 2008)... 

Singlet oxygen was discovered originally by Raab who first reported the photodynamic effect of dyestuffs, light, and oxygen [311]. The biomedical implications of this discovery have only recently been made clear, particularly by Dougherty and his co-workers, who have demonstrated the implications of the photodynamic effect in tumor therapy [312]. 

Recently, a common but specific chemical structural pattern has been observed among a large number of biologically, pharmacologically, and clinically active compounds from both the natural and synthetic origin. This structural pattern may lead to the design of novel molecules with pertinent biomedical implications. A preliminary account of this observation has been published [51]. 

Beppu, T., Park, Y.-N., Aikawa, J., Nishiyama, M., and Horinouchi, S. (1995). Tyrosine 75 on the flap contributes to enhance catalytic efficiency of a fungal aspartic proteinase, Mucor pusillus pepsin. In Aspartic Proteinase Structure, Function, Biology, and Biomedical Implications. Takahashi, T. (Ed.), (pp. 559-563). New York Plenum Press. 

Sola, R.J., Rodriguez-Martinez, J.A., Griebenow, K. Modulation of protein biophysical properties by chemical glycosylation Biochemical insights and biomedical implications. Cell Mol. Life Sci. 2007, 64, 2133-52. 

Y. Kiso in Aspartic Pmteinases Structure, Function, Biology, and Biomedical Implications (Ed. K. Takahashi), Plenum Press,... 

Draget, K. I. and Taylor, C. (2011). Chemical, physical and biological properties of alginates and their biomedical implications. Food Hydrocolloids 25(2), 251-256. 

Gold-Binding to Metallothioneins and Possible Biomedical Implications... 

Highly transmissive, electroactive, and conductive poly[(3,4-alkylenedioxy)pyrrole-2,5-diyl] thin films were prepared by in situ chemical polymerization [36]. The process possesses a significant advantage as environmentally harmful organic solvents are not required since coatings can be obtained directly on the substrate. Many factors such as temperature, pH, nature of dopant, and oxidant were found to influence the film formation. PXDOPs were also synthesized from flexibly functionalized monomers, and showed highly stable aqueous compatibility and therefore unique potential for biomedical implications [37]. 

Thomas, C.A., K. Zong, and P. Schottland. 2000. Poly(3,4-alkylenedioxypyrrole)s as highly stable aqueous-compatible conducting polymers with biomedical implications. Adv Mater 12 222. 

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