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Bioluminescence, receptor assays

Stables, J. Green, A. Marshall, F. et al. A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor. Anal. Biochem. 1997, 252, 115-126. Milligan, G. Rees, S. Chimaeric G alpha proteins their potential use in drug discovery. Trends Pharmacol. Sci. [Pg.3127]

Vidi, P., Watts, V. (2009). Fluorescent and bioluminescent protein-firagment complementation assays in the study of G protein-coupled receptor oligomerization and signaling. Molecular Pharmacology, 75, 733-739. [Pg.130]

Bioluminescence resonance energy transfer (BRET) is a form of Eorster resonance energy transfer (RET). It is the non-radiative transfer of energy from an excited state donor to a ground state acceptor. The efficiency of energy transfer is highly dependent on the distance between the donor and acceptor moieties and their relative orientation with respect to each other. The photon emissions from the donor and receptor molecules during BRET reaction can be measured to quantify assay products. [Pg.97]

See other pages where Bioluminescence, receptor assays is mentioned: [Pg.167]    [Pg.3123]    [Pg.275]    [Pg.275]    [Pg.123]    [Pg.257]    [Pg.98]    [Pg.134]    [Pg.163]    [Pg.249]    [Pg.77]    [Pg.130]    [Pg.130]    [Pg.123]    [Pg.123]    [Pg.151]    [Pg.2755]    [Pg.321]    [Pg.276]   
See also in sourсe #XX -- [ Pg.45 ]



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