Biology and regulation of the immune response

An understanding of the basic principles of the biology of the immune response and its regulation is a prerequisite for the successful experimental production of antibodies. This enables the investigator to induce a vigorous antibody production, instead of obtaining highly unpredictable results and undesired effects, such as tolerance (immune unresponsiveness). 

Some highly recommended reviews are Eisen (1980), Roitt (1980), Benacerraf and Unanue (1981), Golub (1981), and Klein (1982). 

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