Biological processes platelet production

Oleuropein appears to interfere with some biological processes such as lipoprotein oxidation, platelet aggregation, platelet and leukocyte eicosanoid production and cardiovascular control too. As previously described, oleuropein and hydroxy-tyrosol are characterised by a catechol moiety that appears to be needed for their scavenger and antioxidant activities. In fact, it was demonstrated that these compounds prevent thermally initiated autoxidation of methyl linoleate in homogenous solutions [56], protect LDL from oxidation [57] and inhibit production of... 

For instance, sensory properties such as texture and optical appearance are of utmost importance for the quality of food products. In living systems, structures and shapes are strongly related to biological functioning. Examples are the influence of the (local) curvature on the barrier properties of biological membranes, the change of shape of blood platelets in the blood clotting process, the influence of shape (aspect ratio) on the toxicity of nanoparticles, and the dependence of enzymatic activity on the three-dimensional structure of protein molecules. 

Hemoperfusion circulates blood directly over sorbents, such as charcoal or anion exchange resins, or other more complex biochemical reactors, including immobilized enzymatic bioreactors, which allows the chemical processing of specific biologic products. This technique is limited by the loss of other useful substances and can cause complications, such as bleeding when there is an excessive removal of coagulation factors and platelets. To minimize these losses and improve biocompatibility, sorbents can be coated with cellulose to avoid direct contact with blood or plasma, although this in turn reduces the effectiveness of the sorbents. 

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