Bioinformatics gene prediction

Biological databases Sequence alignment Gene prediction Molecular phylogenetics Structural bioinformatics Genomics and proteomics... 

Stanke, M., Schoffmann, O., Morgenstern, B., and Waack, S. (2006) Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources. BMC Bioinformatics 7, 62. 

Wang, J., Bo, T. H., Jonassen, L and Hovig, E. (2003). Tiimor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data. BMC Bioinformatics, 4 60. 

Gabaldon T, Huynen MA (2005) Lineage-specific gene loss following mitochondrial en-dosymbiosis and its potential for function prediction in eukaryotes. Bioinformatics 21 (2) iil44—iil50... 

Bioinformatics uses computers to create and maintain large electronic databases on genomes, protein sequences, and proteomes. With the help of protein prediction software, the computer analysis of genome sequences is producing thousands of new proteins of unknown structure and function. These proteins are called hypothetical proteins because they are predicted from the gene sequence. To know if they really exist would require that they be isolated, purified, and subjected to X-ray crystallography or... 

Korf I, Flicek P, Duan D, Brent MR. Integrating genomic homology into gene structure prediction. Bioinformatics 2001 17(suppl 1) S140—S148. 

Ofiran, Y. and Rost, B., 2005, Predictive methods using protein sequences. In Baxevanis, A.D. and Ouellette, B.F.F. (Eds), Bioinformatics A practical guide to the analysis of genes and proteins, 3rd Edition, Wiley-Interscience, 197-221. 

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