Biochemical engineering controls

Absorption Air pollution Automatic control Biochemical engineering... 

In biochemical engineering processes, measurement of dissolved oxygen (DO) is essential. The production of SCP may reach a steady-state condition by keeping the DO level constant, while the viable protein is continuously harvested. The concentration of protein is proportional to oxygen uptake rate. Control of DO would lead us to achieve steady SCP production. Variation of DO may affect retention time and other process variables such as substrate and product concentrations, retention time, dilution rate and aeration rate. Microbial activities are monitored by the oxygen uptake rate from the supplied ah or oxygen. 

Mathematical modelling, in biochemical engineering, 77 41 Mathematical models of glass melting, 72 605 process-control, 20 687-691 Mathematical optimization approach, in computer- aided molecular design, 26 1037... 

Chemical engineering is no longer confined to purely physical processes and the unit operations, and a number of important new topics, including reactor design, automatic control of plants, biochemical engineering, and the use of computers for both process design and control of chemical plant will be covered in a forthcoming Volume 3 which is in course of preparation. 

Chapter 5, on Biochemical Engineering, has been completely rewritten in two sections by Dr R. L. Lovitt and Dr M. G. Jones with guidance from the previous author, Professor B. Atkinson. The earlier part deals with the nature of reaction processes controlled by micro-organisms and enzymes and is prefaced by background material on the relevant microbiology and biochemistry. In the latter part, the process engineering principles of biochemical reactors are discussed, and emphasis is given to those features which differentiate them from the chemical reactors described previously. 

Ion transport is also often coupled with cellular energy production and with nutrient and product membrane transport. Aside from Papoutsakis work on the influence of methanol transport on growth of methanol-consuming bacteria, the importance of membrane control of nutrient and product fluxes into the cell has been largely ignored by biochemical engineers [25]. Better methods for measuring the pH and electrical potential differences across cell membranes are needed, as is more careful consideration of membrane-mediated processes in cell kinetics models. 

Humphrey, A. E., Algorithmic monitors for computer control of fermentations,//onzons of Biochemical Engineering, (S. Aiba, ed.), p. 203, Tokyo Press, Tokyo (1987)... 

Schmidt, H.-L., Saschewag, I., Possibilities of Process Control with Biosensors , in Biochemical Engineering — A Challenge for Interdisciplinary Cooperation, Chmiel, H., Hammes, W. P., Bailey, J. E. (eds.) Stuttgart Gustav Fischer Verlag, 1987, pp. 132-138. 

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