Bioactive glass particles

Use of 3D foams is also a popular method for bone regeneration applications, although they are most often employed for trabecular bone regeneration [152,154]. There are a few methods utilized to create foams for this application, one of the most popular being a polymer foam replication technique, in which a polymer foam is either electrosprayed or immersed into a HAp/bioactive glass particle slurry in order to fully coat the foam and create a trabecular bone-like aichitecture. However, other methods are also utilized, including creating composite foam solutions that are injectable and form once inside the body [153]. Results of Fu et al. [152] have indicated mechanical properties similar to those of natural trabecular bone. 

Schepers E.J.G, Ducheyne P Barbier L., and Schepers S. 1993. Bioactive glass particles of narrow size range A new material for the repair of bone defects. Impl. Dent. 2 151-156. 

Harmata AJ, et al. Investigating the effects of surface-initiated polymerization of E-caprolactone to bioactive glass particles on the mechanical properties of settable polymer/ceramic composites. J Mater Res 2014 29(20) 2398-407. 

S. Labbaf et al.. Spherical bioactive glass particles and their interaction with human mesenchymal stem cells in vitro. Biomaterials 32(4), 1010-1018 (2011)... 

M. Erol, A.R. Boccaccini, Nanoscaled bioactive glass particles and nanofibres. Bioact. Glasses Mater. Prop. Appl. 129-161 (2011)... 

Fabrication of Nanoscale Bioactive Glass Particles and Fibers 205... 

Figure 6.6 Young s modulus of composites consisting of different concentrations of micron- or nanosized bioactive glass particles in poly(3-hydroxybutyrate) compared to the neat polymer [76],...

Compared with the melt process, the sol-gel route for bioactive glass synthesis is a bottom-up process. This means versatility bioactive glasses can be made as nanoporous (mesoporous) powders/monoliths, submicron/nanoparticles [23], or scaffolds [24]. Figure 43.2 shows a nanoporous surface of a bioactive xerogel and monodispersed bioactive glass particles with diameters of 220 nm. 

S.K. Misra, T. Ansari, D. Mohn, S.P. Valappil, T.J. Brunner, W.J. Stark, et al.. Effect of nanoparticulate bioactive glass particles on bioactivity and cytocompatibility of poly(3-hydroxybutyrate) composites, J. Royal Soc. Interface 7 (2010) 453-465. 

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