Binding dependent multiple-site, variable-affinity

Figure 7.19 Dependent multiple-site variable affinity cooperative binding equilibria, (a) Classical sigmoidal binding isotherms indicative of ligand-receptor interactions that involve strong positive cooper-ativity. Curves move to right as composite equilibrium constant ff increases, (b) Linear Hill plots derived from sigmoidal data illustrated in (a). Gradients and intercepts define values of n and K respectively.

---