Bidirectional Synthesis of Carbohydrate Libraries

The quality of this library was examined by monosaccharide compositional analysis. A portion of the trisaccharide library was treated with aqueous trifluroacetic acid at 100°C for 4 h. Analysis of the resulting mixture of monosaccharides on a Dionex HPLC system with a PA1 column and pulsed amperometric detection (PAD) showed that galactose, glucose, and mannose were present in approximately the required ratio. 

Edited by Peter H. Seeberger Copyright 2001 John Wiley Sons, Inc. ISBNs 0-471-37828-3 (Hardback) 0-471-22044-2 (Electronic) 

11 Carbohydrate Libraries in Solution Using Thioglycosides From Multistep Synthesis to Programmable, One-Pot Synthesis 

Texas A M University, College Station, Texas CHI-HUEY WONG 

20 amino add building blocks 1 site for connectivity Linear connectivity 

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