Bicyclo nonanediones

N-Nitroso N phenylglycine, 46, 96 reaction with acetic anhydride to yield 3 phenylsydnone, 46, 96 Nitrosyl chloride, addition to bicyclo-[2 2 ljhepta 2,5 diene, 46, 75 2,4-Nonanedione, 47, 92 Nonane, 1,1,3 trichloro-, 46,104 Nortricyclanol, 46, 74 oxidation by chromic acid, 46, 78 Nortricyclanone, 46, 77 Nortncj clyl acetate 46, 74 frombicyclo[2 2 ljhepta 2,5 dieneand acetic acid, 46, 74 saponification of, 46, 75... 

Finally, 2,6-disubstituted adamantanes may be obtained either by direct synthesis or as minor components of specific ionic substitution reactions. Treatment of 2,6-bicyclo[3.3.1]nonanedione with pyrolidine and methylene iodide followed by acid hydrolysis provides pure 2,6-adamantanedione (42) in an overall yield of approximately 20 % (Eq. (76)) 288>. 

Nonanedioic add, 5-hydroxy-2,4,6,8-tetramethyl- diastereoselective lactonization, 168, 327-328 2,4-Nonanedione retro-synthesis, 204 Norbomane etc. See Bicyclo[2.2.1 ] heptane ere. Norphedrine = (/ , S )-a-benzene-methanol, ( + H S)- chiral auxiliary, 61 —, ( ) synthesis, 302 Norgestrel, ( )- total synth., 278 19-Norpregna-1,3,5(10)-trien-2-yne-3,l 7-diol, (17a)- [ethynylestradiofy 62-63 A-Norpregn-3(5)-eri-20-one, 3-methyl- synthesis, 91-92, 279-280 Noyori hydrogenation, 102-103, 325-326 SI Nuclease, 242... 

Org. Chem.,69,1948 (2004). Determination of Absolute Configuration Using Concerted Ab Initio DFT Calculations of Electronic Circular Dichroism and Optical Rotation Bicyclo [3.3.1] nonanediones. 

Enamines of cyclohexylamine have been enantioselectively cyclized to bicyclo[3.3.1] nonanedione systems, using acryloyl chloride and chiral pyrrolidine catalysis. Enantio-pure A-sulflnylimines have been used in asymmetric synthesis of isoquinolone alkaloids, and a stereocontrolled synthesis of 3,4,5,6-tetrahydropyrimidine-based amino acids from imino ethers has been reported. Diastereoselective additions of chiral acetals of (2-lithiophenyl)acetaldehyde to arylimines have been used in an asymmetric synthesis of 1-aryltetrahydroisoquinolines. " Organolithiums react with chiral imines, in the presence of Lewis acids or bases, to give amines in up to 100% de. Diastereoselective additions of copper reagents to imines derived from (5)-l-phenylethylamine have been reported. 

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See also in sourсe #XX -- [ , ]

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