Chiral imines

Keywords Asymmetric hydrosilylation, optically active alcohols, amines, Chiral Titanocene Catalysts, Acyclic Imines, Cyclic Imines, Chiral Rhodium Catalysts, aromatic ketones... 

CuPFft, bis(imine) (chiral) CuOTf, bis(imine) (chiral) CuOTf, bis(oxazoline) (chiral)... 

R2CHCOS 3 /BC13 SMe2. chiral amino alcohol /base /imine (chiral)... 

Homoenolate and homoallenyl carbanion equivalents. Two routes to homo-cnolate species are based on the action of (propene)titanium diisopropoxide. Trialkoxy-titanates generated from acetals of acrolein react with aldehydes and imines. Chiral cyclic acetals are similarly cleaved to afford the nucleophiles. 3-Alkoxy-2-propyn-l-yl carbonates are transformed into (l-alkoxyallen)-l-yltitanates that add to carbonyl compounds with y-selectivity. ... 

Extension of this methodology to a triple stereoselective process is reported in reaction D. This completely stereoselective reaction takes advantage of the matching combination between the enolate and the imine chiral auxiliary, which, in its turn is also internally matched with the other imine stereocenter [37]. 

Keywords, Asymmetric reaction, Organoiithium, Conjugate addition, Imine, Chiral hgand... 

Cycloaddition of diverse types of ketenes and imines leading to the formation of P-lactams is reported. The reactions of chiral ketenes with achiral imines, chiral imines with achiral ketenes, chiral imines with chiral ketenes, and catalytic asymmetrical Staudinger reactions have been investigated. In general, a higher level of asymmetric induction is achieved using either chiral ketenes or chiral imines derived from chiral aldehydes in comparison to the use of a chiral imine derived from an achiral aldehyde with an achiral ketene. Both carboxylic acid chlorides and carboxylic acids themselves have been used as ketene precursors. 

---