Berthier, Pierre

Louis Kuslan, Berthier, Pierre, pp. 72-73 in Dictionary of Scientific Biography, Charles Scribner s Sons, New York, 1970-1980. 

Dhainaut, A., Regnier, G., Atassi, G., Pierre, A., Leonce, S., Kraus-Berthier, L. and Prost, J.F. (1992) New triazine derivatives as potent modulators of multidrug resistance. Journal of Medicinal Chemistry, 35, 2481-2496. 

Leonce S, Kraus-Berthier L, Golsteyn RM, David-Cordonnier MH, Tardy C, Lansiaux A, Poindessous V, Larsen AK, Pierre A. (2006) Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1. Cancer Res 66 7203-7210. 

Ramuz H, Schmutz W, Huber R (1989) Eur J Med Chem 24 493 Boesch D, Gaveriaux C, Jachez B, Pourtier-Manzanedo A, Bollinger P, Loor F (1991) Cancer Res 51 4226 Dhain-aut A, Regnier G, Atassi G, Pierre A, Leone S, Kraus-Berthier L, Prost J-F (1992) J Med Chem 35 2481... 

In 1962, Pierre Eymard, a graduate smdent at the University of Lyon, synthesized a series of khellin derivatives. Khellin is a biologically active substance that occurs in the fruit of the wild Arabian Khell plant and which has been used for centuries by herbalists for the treatment of kidney stones. Eymard arranged to have his new compounds biologically evaluated at the Ecole de Medecine et de Pharmacie in nearby Grenoble. When attempts to produce a solution of these khellin compounds failed, advice was sought from H. Meunier of the nearby Laboratoire Berthier. In view of Berthier s recent peripheral interest in valproic acid as a solvent for bismuth compounds, Meunier recommended valproic acid as a nontoxic inert solvent. 

Peglion JL, Aasssi G, Pierre A, Kraus-Berthier L, Guilbaud N, Vilaine JP (1995) 1,4-Dihydropyridine compounds. US Patent 5 389 644... 

JMC2481 A. Dhainaut, G. Regnier, G. Atassi, A. Pierre, S. Leonce, L. Kraus-Berthier and J. F. Prost ... 

Pierre A, Dunn TA, Kraus-Berthier L, Leonce S, Saint-Dizier D, Regnier G, Dhainaut A, Berlion M, Bizzari JP, Atassi G. In vitro and in vivo circumvention of multidrug resistance by Servier 9788, a novel triazinoaminopiperidine derivative. Invest New Drug 1992 10 137-148. 

Pierre Berthier (Nemours 3 July 1782-29 August 1861), general inspector of the Corps des Mines, published a large number of papers on mineral... 

It is not the word alumine which has come to designate aluminium ore, but the word bauxite . This is because in 1821 Pierre Berthier (1782-1867), a mining engineer, discovered that the red soil of the village Les-Baux-de-Provence contained 40-50% alumina, the rest being comprised essentially of iron oxide, Fe304 (the source of its red colour), and sihca, Si02. 

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