Benzylamines plots

Figure 2. Plot of log ks vs % modifier for benzylamine on 4 different stationary phases. 40°C, 182 bar (outlet).

Figure 6. Plots of log k vs solvent strength (Ejsjr) for 3 benzylamines at...

Mechanisms have been suggested for the N-bromosuccinimide (NBS) oxidation of cyclopentanol and cyclohexanol, catalysed by iridium(III) chloride,120 of ethanolamine, diethanolamine, and triethanolamine in alkaline medium,121 and for ruthenium(III)-catalysed and uncatalysed oxidation of ethylamine and benzylamine.122 A suitable mechanism has been suggested to explain the break in the Hammett plot observed in the oxidation of substituted acetophenone oximes by NBS in acidic solution.123 Oxidation of substituted benhydrols with NBS showed a C-H/C-D primary kinetic isotope effect and a linear correlation with er+ values with p = —0.69. A cyclic transition state in the absence of mineral acid and a non-cyclic transition state in the presence of the acid are proposed.124 Sulfides are selectively oxidized to sulfoxides with NBS, catalysed by ft-cyclodextrin, in water. This reaction proceeds without over-oxidation to sulfones under mild conditions.125... 

FIGURE 10.22 Electropherograms of the products following on-chip tryptic digestion of bovine insulin B-chain at 37°C. The flow in the reaction channel was stopped for different times to study the effect on the reaction. Control runs (see the flat curves) without insulin B-chain were performed in the continuous flow mode and in a flow with a stop time of 6 min. The arrows indicate the migration time of benzylamine, which was added as an EOF marker. All electropherograms are plotted on the same scale with an offset for clarity [1058]. Reprinted with permission from Elsevier Science. 

Moat reoently Addy and co-workcrs made the notable discovery that the normal reaction .e. terminal attack) of benzylamine with p-substituted styrene oxides exhibits a positive p-value in the Hammett plot, while the abnormal reaction ( , , bonxylio attack) exhibits a negative /i-value. These faots are consistent with a transition state of appreciable earbonium ion character fw the latter reaction. 

The eq.(5) means that the intercept of the linear plot of log ([ BD+] / [B] ) vs. pXa,BD+ gives the pATa of zinc-bound D2O. Figure 5 shows the relation between log ([ BD+] / [B] ) calculated from the chemical shifts of NMR spectra in DMSO-tfe S. pATa,BD+. The weak base B are triethylamine, benzylamine, morpholine, 2-methylimidazole, 7V-methy-morpholine, and 2,6-lutidine. The pATa value of zinc-bound water molecule for 7 was ca. 8.6,... 

The following test systems were selected Lewis acids-. Boron trifluoride etherate, titanium tetrachloride, aluminum trichloride, zinc dichloride, and zinc diiodide Amines Benzylamine, butylamine, morpholine, and dipropylamine. The distribution of these items in the corresponding score plots are shown in Fig. 16.7. 

Figure 5 Plots for a set of 22 benzylamines. (a) Experimental vs. predicted values of pK. (b) Random test results.

Figure 11-23 Plot of NMR binding (l/Ti) ( A-) versus iV-all l hydrophobic fiagment constants compared with an overlay plot of computed interaction energies vs 7V-alkyl hydrophobic fragment constants (- -) for benzylamines R = H to R = CgHn (reproduced from [100] with permission from Wiley-VCH, D-69451 Weinheim, Germany...

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