Amines benzylamines

The A-acetyl derivatives of the 2-alkylthio-l,3-thiadiazol-4-imines (124, R = SR, R = Ac) undergo nucleophilic displacement reaction with amines (benzylamine, cyclohexylamine, morpholine, or aniline) giving the 2-amino derivatives (124, R = NRj, R = Ac). The salt (126, R = R = Ph, R = R = H, X = Cl) reacts with aniline at room temperature giving 4-anilino-2-phenyl-l,3-thiazole (128), presumably by a mechanism involving cleavage of the heterocyclic ring. ... 

Formation of an amide is also indicated in the reaction of PCTFE with Cr(CO)6 and the primary amine, benzylamine. The infrared absorption spectrum shows an N-H stretch centered at 3400 cm, aromatic C-H stretches at 3063 and 3030 cm1, aliphatic C-H stretches at 2933 and 2876 cm1, a broad amide I/amide II band ranging from 1680-1580 cm1, and a C-N stretch at 1454 cm1. The C-Cl stretch at 970 cm1 also shows a significant decrease in... 

The synthesis of a number of substituted thioureides by treatment of isothiocyanates 2 and 30-32 with aniline, 2-aminopyridine, 1-adamantyl-amine, benzylamine, 2-aminobenzimidazole, 2-aminobenzothiazole, o-bromoaniline, 2-aminopyridine, 5-amino-1 -phenylpyrazole-4-carboxylic acid, and various classes of sulfamines, in benzene or xylene solution, has been reported.54... 

Homogeneous hydrogenation of nitriles, Saturated nitriles are hydrogenated to primary amines in 67-100% yield with 1 as catalyst in THF. The catalytic activity of 1 for aromatic nitriles is not so high as for hydrogenation of aliphatic nitriles. The C=C bond of unsaturated nitriles is reduced more readily than the C=N bond. This catalyst is also eflective for dehydrogenation of amines (benzylamine — benzonitrile, 27% yield). 

In a paired electrolysis, amines have been A -alkylated in alcoholic solution. At the Pt(Pt) anode the alcohol was oxidized to an aldehyde that condensed with the amine to an imine the imine was reduced at the cathode to a secondary amine. Benzylamine was thus electrolyzed to benzylethylamine in 96% yield (65% current yield) in ethanol containing 10 vol% of water [14]. 

The following test systems were selected Lewis acids-. Boron trifluoride etherate, titanium tetrachloride, aluminum trichloride, zinc dichloride, and zinc diiodide Amines Benzylamine, butylamine, morpholine, and dipropylamine. The distribution of these items in the corresponding score plots are shown in Fig. 16.7. 

The presumed stereochemistry of displacement of chlorine at a phosphoryl centre by a primary amine (benzylamine) and crystallographic determination of the configuration of 2-benzylamino-4-phenyl-l,3,2-dioxaphosphorinane 2-oxide has allowed an assignment of stereochemistry (trans chlorine and phenyl) in a diastereoisomeric 2-chloro-4-phenyl-l,3,2-dioxa-phosphorinane 2-oxide the more stable of the two cyclic phosphoryl chlorides has chlorine in the axial position. 

AI3-26794 Araldite accelerator 062 BDMA Benz-enemethanamine, N,N-dimethyl- Benzyl-N,N-dimethyl-amine Benzylamine, N,N-dimethyl- Benzyldimethyl-amine N-Benzyldimethylamine N-Benzyl-N,N-dimethyl-amine CCRIS 6693 Dabco B-16 Dimethyl-benzylamine N,N-Dimethylbenzylamine N,N-Dimethyl-N-benzylamine N,N-Dimethylbenzenemethanamine EINECS 203-149-1 NSC 5342 Pentamin BDMA N-(Phenylmethyl)dimethylamine Sumine 2016 UN2619. Amine-based catalyst for flexible slabstock PU foam. Used as a polyurethane catalyst and an epoxy curing agent. Liquid mp = -75° bp = 181° d° = 0.915 7.m = 252, 268, 265 nm (cyclohexane) slightly soluble in H2O, freely soluble in EtOH, Et20 LD50 (rat orl) = 265 mg/kg. Air Products Chemicals Inc. Pentagon Chems. Ltd. -... 

Figure 13 Scheme of the proposed catalytic cycle of copper-containing amine oxidases (CuAOs), TPQ is the cofactor 2,4,5-trihydroxy-phenylalanine quinone, which is derived from a constitutive Tyr that is part of the polypeptide of the enzyme (E). The substrate shown is the aromatic primary amine, benzylamine, a typical substrate of some amine oxidases, such as CuAO from E. coli (ECAO). Reproduced from B. J. Brazeau B. J. Johnson C. M. Wilmot, Arch. Biochem. Biophys. 2004, 428, 22-31, with permission from Elsevier Inc. 

Morpholine (B) is the stronger base (pKb 5.79). It has a basicity comparable to that of secondary aliphatic amines. FVridine (A), a heterocyclic aromatic amine pl 8.75), is considerably less basic than aliphatic amines. Benzylamine (D), a primary aliphatic amine, is the stronger base (p/Cj, 3-4). o-Toluidine (C), an aromatic amine, is the weaker base (pKb 9-10). In the absence of Table 10.2, one can see that the electron pair on nitrogen in o-toluidine can participate in resonance with the benzene ring, while there are no resonance possibilities in benzylamine.This results in o-toluidine s electron pair being less available for reaction with an acid. 

Alcohols benzylic, aliphatic, secondary Amines benzylamines, secondary amines, anilines CuAI-HT recoverable 1st cycle, 98% 5th cycle, 97%... 

A similar mechanism has been proposed for the oxidation of secondary amines to imines using catalytic Ru2( i-02CMe) Cl and O2 in toluene [108]. The substrate scope includes a number of five- and six-membered cyclic amines, including tetrahydroquinolines, tetrahydroisoquinolines, and indolines. Dibenzylamine converted cleanly to the imine. Of interest, the primary amine benzylamine is oxidized completely to benzonitrile. Several monoruthenium complexes were also evaluated for catalysis, but their reaction yields were significantly lower, supporting an intact diruthenium catalyst. 

Classification Aliphatic amine benzylamine Empirical CoH. N Formula C.HjCH(CH3)NH2... 

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