Benzo pyrrolizidine

Pandey, G., Sridhar, M., and Bhalerao, U.T. (1990) Regiospecfic dihydroindoles directly from p-arylethylamines by photoinduced SET reaction one-pot wavelength switch approach to benzo-pyrrolizidines related to mitomycin. Tetrahedron Letters, 31, 5373-5376. 

The chemistry of pyrrolizines has previously been reviewed only incidentally in reviews of pyrrolizidine alkaloids.7 The present review includes pyrrolizine and dihydropyrrolizines as well as their benzo derivatives. Azapyrrolizines, reviewed recently,8 are only occasionally mentioned. The literature is covered to the end of 1982. 

Deboronation of 1 with methanol and/or aqueous NaOH gave 2-allylindoline 2 (82%). The latter was transformed into benzo[f]pyrrolizidine 3 via hydroboration-oxidation-cyclization sequence2-5. 

Pyrrolizidine alkaloids, chemistry and toxicology of 86MI9. Quaternary benzo[c]phenanthridine alkaloids 90CCC2840. Quinolizidine alkaloids 87WCH393. 

AckreU, J., F. Franco, R. Greenhouse et al. 1980. New heterocyclic systems. Benzo[4,5] cyclohepta[l,2-f>]pyirole and benzo[5,6]cyclohepta[l,2-f]pyrrolizidine derivatives. J Heterocycl Chem 17 1081-1086. 

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