Benign peripheral nerve sheath tumors

Determinants associated with non-neoplastic Schwann cells and benign peripheral nerve sheath tumors are frequently detected in MPNSTs. They show reactivity for... 

Benign Peripheral Nerve Sheath Tumors and Ganglioneuromas... 

For cancer smdies, several models are available, e.g., to study neurofibromatosis which affects about 1 in 3500 individuals worldwide. Neurofibromatosis type 1 (NFl) is a prevalent familial cancer syndrome resulting from germline mutations in the NFl tumor suppressor gene. Hallmark features of the disease are the development of benign peripheral nerve sheath tumors (neurofibromas), which can progress to malignancy. Unlike humans. 

NF1 neurofibromatosis type 1 benign and malignant peripheral nerve sheath tumors... 

Gray MH, Rosenberg AE, Dickersin GR, et al. Glial fibrillary acidic protein and keratin expression by benign and malignant peripheral nerve sheath tumors. Hum Pathol. 1989 20 1089-1096. 

As in any other organ, immunostains can be of great utility in resolving a variety of spindle cell mesenchymal lesions occurring in the prostate including benign and malignant smooth muscle neoplasms, peripheral nerve sheath tumors, and rhabdomyosarcoma (Table... 

This extremely rare benign tumor, usually capsu-lated, arises from the nerve sheaths of peripheral nerves. It presents at ultrasound as a well-defined, hypoechoic rounded mass hypervascularized at color Doppler interrogation (Kousseff and Hoover 1999 Jung et al. 2006). 

---