Bayesian analysis heterogeneous

Cox, C. J., Goffinet, B., Shaw, A. J. and Boles, S. B. (2004) Phylogenetic relationships among the mosses based on heterogeneous Bayesian analysis of multiple genes from multiple genomic compartments. 

Before presenting oin discussion, we present a brief and select overview of some relevant literature. Peto (1987) discusses some foimdational issues in systematic reviews of randomized trials for rare outcomes, in particular the need for such reviews and considerations of heterogeneity of the treatment effect. Hammad et al. (2011) present a thorough overview of the issues associated with the secondary use of randomized trials to evaluate safety. Bradbum et al. (2007) evaluate statistical meta-analysis methods for rare events. Kaizer et al. (2006) present an interesting example of a hierarchical Bayesian method for meta-analysis of safety. Crowe et al. (2009) provide recommendation for a premarket safety program. 

FIGURE 18.1 Phylogram of the most likely tree (-In L = 19561.59688) obtained from the maximum likelihood analysis. Numbers below branches, or to the right when appropriate, indicate heterogeneous Bayesian posterior probabihties ( 5%). 

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