Bacterial siderophores, production

K. Mulya, M. Watanabe, M. Goto, Y. Takikawa, and S. Tsuyuniu, Suppression of bacterial wilt di.sease in tomato by root-dipping with P.seudomonas fluorescens PfG32 The role of antibiotic substances and siderophore production. An. Phytopath. Soc. Jpn. 62 (1996). 

As research continues into the field of siderophore production and iron uptake, the knowledge gained will be invaluable to the development of medical treatments for bacterial infection,... 

The relationship between siderophore production and bacterial growth rates has led to the belief that siderophore prodnction contribntes to bacterial viralence. Rednced viralence of mntants deficient in siderophore production have been reported for Yersinia pestis, the cansative agent of... 

Cyanobacteria were probably the first organisms to perform oxygenic photosynthesis resulting eventually in the oxidation of environmental Fe " to Fe " with all its consequences. To cope with this problem the production of siderophores was initiated. Not much is known about the siderophores of cyanobacteria. Schizokinen (see below under citrate siderophores, Sect. 4.1) (326) found to be produced by several bacterial species may have been acquired by gene transfer see however also the citrate siderophores synechobactins. 

Bacteria have high Fe requirements and account for up to 50% of the biological iron pool in Fe-limited regions (Tortell et al., 1996). Bacterial production is stimulated with the addition of Fe (Pakulski et al., 1996). Under conditions of Fe deprivation, microorganisms release small molecules (MW <1000 Da) called siderophores that chelate Fe(III) with a strong affinity (Neilands, 1981, 1995). In controlled laboratory experiments, both... 

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