Baccharis coridifolia

Rosso, L., Maier, M. S., and Bertoni, M. D. (2000). Trichothecenes production by the Hypo-crealean epibiont of Baccharis coridifolia. Plant Biol. (Stuttg.) 2, 684-686. 

Two non-macrocyclic trichothecenes, 8-deoxotrichothecinol A(Table 1 C19H26O5), from Holarrhena floribunda, and miotoxin G (Table 1 C29H40O9), from Baccharis coridifolia, are plant products (but see Notes to Tables 1-4). 

Rizzo I, Varsavky E, Haidukowski M, Frade H (1997) Macrocyclic Trichothecenes in Baccharis coridifolia Plants and Endophytes and Baccharis arterrdsioides Plants. Toxicon 35 753... 

Busam L, Habermehl GG (1982) Accumulation of Mycotoxins by Baccharis coridifolia A Reason for Livestock Poisoning. Naturwiss 69 392... 

Habermehl GG, Busam L, Heydel P, Mebs D, Tokamia CH, Dobereiner J, S nxml M (1985) Macrocyclic Trichothecenes Cause of Livestock Poisoning by the Brazilian Plant Baccharis coridifolia. Toxicon 23 731... 

Habermehl GG, Busam L (1984) Miotoxin B and C, zwei neue macrocyclische Trichothecene aus Baccharis coridifolia DC. Liebigs Ann Chem 1746... 

Bertoni MD, Cabral D (1991) Ceratopycnidium baccharidicola sp. nov. from Baccharis coridifolia in Argentina. Mycol Res 95 1014... 

Rosso ML, Maier MS, Bertoni MD (2000) Macrocyclic Trichothecene Production by the Fungus Epibiont of Baccharis coridifolia. Molecules 5 345... 

Busam, L., and G. G. Habermehl Accumulation of mycotoxins by Baccharis coridifolia A reason for livestock poisoning. Naturwissenschaften 69, 392 (1982). 

Trichothecenes are a series of sesquiterpene compounds that have been isolated either as fungal metabolites or from the Brazilian shrubs Baccharis megapotomica and Baccharis coridifolia. The first... 

However, the most interesting of the Baccharis species is most certainly B. coridifolia. This plant is well-known in Brazil as being one of that country s most toxic plants (49) and is a serious hazard to livestock who graze in pastures populated by B. coridifolia (49). Four separate collections were made of B. coridifolia (48). Three of these collections were "From several miles outside Curitaba and a fourth collection in a pasture near Santa Maria, the site of an earlier collection of 13. coridifolia (47), and several hundred miles away from Curitaba. ThTs latter collection and two of the three former collections contained appreciable quantities of roridins A and E. A third collection from near Curitaba appeared to contain no macrocyclic trichothecenes. From a 20 g sample of one of the collections of B. coridifolia... 

Our findings suggest that some Baccharis species form an association with Myrothecium species which produce roridins. These roridins are taken up by the plant and, in the case of B. coridifolia stored, but in the case of B. megapotamTca the roridins are oxidized (metabolized) (45) to the baccharinoids. 

The shrub Baccharis artemisioides is a new source of the known fungal macrocycles verrucarins A and J, and roridins A, D and E, as is the Baccharis spp. endophyte Ceratopycnidium baccharidicola 164). B. megapotamica and B. coridifolia remain the only sources of the baccharinoids. 

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